Micrornas and Long Non-Coding Rnas Affect the Mechanisms Involved in Age-Related Neurodegeneration in a Manner Depending on Rna-Binding Proteins

Micrornas and Long Non-Coding Rnas Affect the Mechanisms Involved in Age-Related Neurodegeneration in a Manner Depending on Rna-Binding Proteins Publisher Pubmed

Hashemi M ; Shafiei Asheghabadi P ; Moassesfar M ; Mashhadikhan S ; Nasirzade S ; Vasheghani Farahani A ; Mehdizadeh S ; Minaei S ; Rahmani M ; Jamshidian F ; Farahani N ; Reiter RJ ; Taheriazam A ; Hasani Sadi F Show All Authors

Hashemi M
Shafiei Asheghabadi P
Moassesfar M
Mashhadikhan S
Nasirzade S
Vasheghani Farahani A
Mehdizadeh S
Minaei S
Rahmani M
Jamshidian F
Farahani N
Reiter RJ
Taheriazam A
Hasani Sadi F
Hushmandi K
Alimohammadi M
Rahimzadeh P
Entezari M

Source: Molecular Neurobiology Published:2026

Abstract

Neurodegenerative diseases (NDs), including Alzheimer’s disease (AD), Parkinson’s disease (PD), amyotrophic lateral sclerosis (ALS), and Huntington’s disease (HD), are marked by progressive neuronal loss and aberrant protein aggregation, presenting substantial global healthcare challenges. Recent research has illuminated the pivotal roles of RNA-binding proteins (RBPs) and non-coding RNAs (ncRNAs), notably microRNAs (miRNAs) and long non-coding RNAs (lncRNAs), in the molecular pathogenesis of age-related neurodegeneration. RBPs orchestrate RNA metabolism and engage extensively with miRNAs and lncRNAs to modulate gene expression at the post-transcriptional level. Dysregulation of these interactions precipitates pathological phenomena such as protein misfolding, stress granule formation, and disrupted RNA processing, thereby exacerbating neuronal dysfunction and death. Specific miRNAs have been implicated in regulating key neurodegenerative biomarkers, including tau and amyloid-β in AD, motor neuron maintenance in ALS, and survival pathways in HD. Elucidating the intricate interplay between RBPs and ncRNAs holds significant promise for the development of therapeutic strategies aimed at ameliorating RNA-mediated mechanisms in neurodegenerative disorders. © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2026.

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Fatemeh Nabavizadeh Rafsanjani (2)

Mahdi Sharif-Alhoseini (1)

Style	Citing Format
MLA	Hashemi M, et al.. "Micrornas and Long Non-Coding Rnas Affect the Mechanisms Involved in Age-Related Neurodegeneration in a Manner Depending on Rna-Binding Proteins." Molecular Neurobiology, vol. 63, no. 1, 2026, pp. -.
APA	Hashemi M, Shafiei Asheghabadi P, Moassesfar M, Mashhadikhan S, Nasirzade S, Vasheghani Farahani A, Mehdizadeh S, Minaei S, Rahmani M, Jamshidian F, Farahani N, Reiter RJ, Taheriazam A, Hasani Sadi F, Hushmandi K, Alimohammadi M, Rahimzadeh P, Entezari M (2026). Micrornas and Long Non-Coding Rnas Affect the Mechanisms Involved in Age-Related Neurodegeneration in a Manner Depending on Rna-Binding Proteins. Molecular Neurobiology, 63(1), -.
Chicago	Hashemi M, Shafiei Asheghabadi P, Moassesfar M, Mashhadikhan S, Nasirzade S, Vasheghani Farahani A, Mehdizadeh S, et al.. "Micrornas and Long Non-Coding Rnas Affect the Mechanisms Involved in Age-Related Neurodegeneration in a Manner Depending on Rna-Binding Proteins." Molecular Neurobiology 63, no. 1 (2026): -.
Harvard	Hashemi M et al. (2026) 'Micrornas and Long Non-Coding Rnas Affect the Mechanisms Involved in Age-Related Neurodegeneration in a Manner Depending on Rna-Binding Proteins', Molecular Neurobiology, 63(1), pp. -.
Vancouver	Hashemi M, Shafiei Asheghabadi P, Moassesfar M, Mashhadikhan S, Nasirzade S, Vasheghani Farahani A, et al.. Micrornas and Long Non-Coding Rnas Affect the Mechanisms Involved in Age-Related Neurodegeneration in a Manner Depending on Rna-Binding Proteins. Molecular Neurobiology. 2026;63(1):-.
BibTex	@article{ author = {Hashemi M and Shafiei Asheghabadi P and Moassesfar M and Mashhadikhan S and Nasirzade S and Vasheghani Farahani A and Mehdizadeh S and Minaei S and Rahmani M and Jamshidian F and Farahani N and Reiter RJ and Taheriazam A and Hasani Sadi F and Hushmandi K and Alimohammadi M and Rahimzadeh P and Entezari M}, title = {Micrornas and Long Non-Coding Rnas Affect the Mechanisms Involved in Age-Related Neurodegeneration in a Manner Depending on Rna-Binding Proteins}, journal = {Molecular Neurobiology}, volume = {63}, number = {1}, pages = {-}, year = {2026} }
RIS	TY - JOUR AU - Hashemi M AU - Shafiei Asheghabadi P AU - Moassesfar M AU - Mashhadikhan S AU - Nasirzade S AU - Vasheghani Farahani A AU - Mehdizadeh S AU - Minaei S AU - Rahmani M AU - Jamshidian F AU - Farahani N AU - Reiter RJ AU - Taheriazam A AU - Hasani Sadi F AU - Hushmandi K AU - Alimohammadi M AU - Rahimzadeh P AU - Entezari M TI - Micrornas and Long Non-Coding Rnas Affect the Mechanisms Involved in Age-Related Neurodegeneration in a Manner Depending on Rna-Binding Proteins JO - Molecular Neurobiology VL - 63 IS - 1 SP - EP - PY - 2026 ER -

Style

Citing Format

MLA

Hashemi M, et al.. "Micrornas and Long Non-Coding Rnas Affect the Mechanisms Involved in Age-Related Neurodegeneration in a Manner Depending on Rna-Binding Proteins." Molecular Neurobiology, vol. 63, no. 1, 2026, pp. -.

APA

Hashemi M, Shafiei Asheghabadi P, Moassesfar M, Mashhadikhan S, Nasirzade S, Vasheghani Farahani A, Mehdizadeh S, Minaei S, Rahmani M, Jamshidian F, Farahani N, Reiter RJ, Taheriazam A, Hasani Sadi F, Hushmandi K, Alimohammadi M, Rahimzadeh P, Entezari M (2026). Micrornas and Long Non-Coding Rnas Affect the Mechanisms Involved in Age-Related Neurodegeneration in a Manner Depending on Rna-Binding Proteins. Molecular Neurobiology, 63(1), -.

Chicago

Hashemi M, Shafiei Asheghabadi P, Moassesfar M, Mashhadikhan S, Nasirzade S, Vasheghani Farahani A, Mehdizadeh S, et al.. "Micrornas and Long Non-Coding Rnas Affect the Mechanisms Involved in Age-Related Neurodegeneration in a Manner Depending on Rna-Binding Proteins." Molecular Neurobiology 63, no. 1 (2026): -.

Harvard

Hashemi M et al. (2026) 'Micrornas and Long Non-Coding Rnas Affect the Mechanisms Involved in Age-Related Neurodegeneration in a Manner Depending on Rna-Binding Proteins', Molecular Neurobiology, 63(1), pp. -.

Vancouver

Hashemi M, Shafiei Asheghabadi P, Moassesfar M, Mashhadikhan S, Nasirzade S, Vasheghani Farahani A, et al.. Micrornas and Long Non-Coding Rnas Affect the Mechanisms Involved in Age-Related Neurodegeneration in a Manner Depending on Rna-Binding Proteins. Molecular Neurobiology. 2026;63(1):-.

BibTex

@article{ author = {Hashemi M and Shafiei Asheghabadi P and Moassesfar M and Mashhadikhan S and Nasirzade S and Vasheghani Farahani A and Mehdizadeh S and Minaei S and Rahmani M and Jamshidian F and Farahani N and Reiter RJ and Taheriazam A and Hasani Sadi F and Hushmandi K and Alimohammadi M and Rahimzadeh P and Entezari M}, title = {Micrornas and Long Non-Coding Rnas Affect the Mechanisms Involved in Age-Related Neurodegeneration in a Manner Depending on Rna-Binding Proteins}, journal = {Molecular Neurobiology}, volume = {63}, number = {1}, pages = {-}, year = {2026} }

RIS

TY - JOUR
AU - Hashemi M
AU - Shafiei Asheghabadi P
AU - Moassesfar M
AU - Mashhadikhan S
AU - Nasirzade S
AU - Vasheghani Farahani A
AU - Mehdizadeh S
AU - Minaei S
AU - Rahmani M
AU - Jamshidian F
AU - Farahani N
AU - Reiter RJ
AU - Taheriazam A
AU - Hasani Sadi F
AU - Hushmandi K
AU - Alimohammadi M
AU - Rahimzadeh P
AU - Entezari M
TI - Micrornas and Long Non-Coding Rnas Affect the Mechanisms Involved in Age-Related Neurodegeneration in a Manner Depending on Rna-Binding Proteins
JO - Molecular Neurobiology
VL - 63
IS - 1
SP -
EP -
PY - 2026
ER -

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Abstract