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The Association of Inflammatory Markers, Il-1 Α and Tgf- Β, With Dietary Insulin Load and Dietary Insulin Index in Overweight and Obese Women With Healthy and Unhealthy Metabolic Phenotypes: A Cross-Sectional Study Publisher Pubmed



Noori S1 ; Mirzababaei A2 ; Shiraseb F2 ; Bagheri R3 ; Clark CCT4 ; Wong A5 ; Suzuki K6 ; Mirzaei K2
Authors
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Authors Affiliations
  1. 1. Department of Nutrition, Science and Research Branch, Islamic Azad University, Tehran, Iran
  2. 2. Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences (TUMS), Tehran, Iran
  3. 3. Department of Exercise Physiology, University of Isfahan, Isfahan, Iran
  4. 4. Centre for Intelligent Healthcare, Coventry University, Coventry, CV1 5FB, United Kingdom
  5. 5. Department of Health and Human Performance, Marymount University, Arlington, United States
  6. 6. Faculty of Sport Sciences, Waseda University, 2-579-15 Mikajima, Tokorozawa, Saitama, 359-1192, Japan

Source: International Journal of Clinical Practice Published:2022


Abstract

Context Research has shown IL-1α might play a role in the associations between the MH group and DII and DIL. Objective. We evaluated the association of inflammatory markers, IL-1α and TGF-β, with dietary insulin load and index in women with healthy and unhealthy obesity phenotypes. Materials and Methods. 228 obese/overweight women aged 18-48 years were included in this study. Biochemical factors were obtained from blood samples. Body composition, anthropometric measures, and physical activity assessments were performed. Dietary intakes, DII, and DIL were assessed. Results. Significant associations were observed between the MH group and the DII group (OR = 2.142, 95% CI = 1.421, 2.850, and p = 0.040), in which IL-1α may play a role. Discussion and Conclusion. Significant associations were observed between the MH group and DII. IL-1α might play a role in these associations. © 2022 Sahar Noori et al.
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