In Vivo Antibacterial and Wound Healing Activities of Roman Chamomile (Chamaemelum Nobile)

In Vivo Antibacterial and Wound Healing Activities of Roman Chamomile (Chamaemelum Nobile) Publisher Pubmed

Kazemian H^{1, 2} ; Ghafourian S¹ ; Sadeghifard N¹ ; Houshmandfar R³ ; Badakhsh B⁴ ; Taji A⁵ ; Shavalipour A⁶ ; Mohebi R¹ ; Ebrahimsaraie HS⁵ ; Houri H⁶ ; Heidari H^{5, 7}

Show Affiliations

1. Clinical Microbiology Research Center, Ilam University of Medical Sciences, Ilam, Iran
2. Department of Medical Microbiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
3. Faculty of Veterinary Medicine, Ilam University, Ilam, Iran
4. Department of Internal Medicine, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran
5. Department of Bacteriology and Virology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
6. Department of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
7. Department of Microbiology, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

Source: Infectious Disorders - Drug Targets Published:2018

Abstract

Background: Today considerable number of drugs are produced from plants. Several plants with antibacterial and healing applications are used in medicine such as Roman chamomile (Chamaemelum nobile L.). Wound infection is one of the most prevalent infections among infectious diseases around the world. Due to appearance of drug resistance, researchers are now paying attention to medicinal plants. Therefore, this study was designed to investigate the antimicrobial and wound healing properties of C. nobile against Pseudomonas aeruginosa using in vivo conditions. Methods: Ethanolic extract of C. nobile was provided using standard method. The 5% C. nobile ointment was prepared by dissolving lyophilized extract in eucerin. Forty five male rats were obtained from Ilam university. After anesthetization and wound creation, wounds were infected by P. aeruginosa. The rats were divided into three groups, group I was treated with C. nobile ointment, group II was treated with tetracycline ointment and the third group was treated with base gel as control group. Results: Antibacterial and wound healing activities of C. nobile ointment were more than tetracycline ointment significantly. Our results indicated that extract of C. nobile had effective antibacterial activity and accelerated the progression of wound healing. Conclusion: Our study indicated that antibacterial and wound healing activities of C. nobile ointment were notable. C. nobile therapy in combination with antibiotics can also be useful because medicinal plants contents operate in synergy with antibiotics. These results revealed the value of plant extracts to control antibiotic resistant bacteria in wound infections. © 2018 Bentham Science Publishers.

Related Docs

1. Evaluation of Biofilm Formation Among Klebsiella Pneumoniae Isolates and Molecular Characterization by Eric-Pcr, Jundishapur Journal of Microbiology (2016)

2. Histopathological Evaluation of the Healing Effects of Human Amniotic Membrane Transplantation in Third-Degree Burn Wound Injuries, Comparative Clinical Pathology (2016)

3. Medicinal Plant and Their Bioactive Phytochemicals in the Treatment of Recurrent Aphthous Ulcers: A Review of Clinical Trials, Pharmacognosy Reviews (2018)

4. The Effect of Matricaria Chamomilla (Chamomile) Extract in Orabase on Minor Aphthous Stomatitis, a Randomized Clinical Trial, Journal of Herbal Medicine (2015)

Experts (# of related papers)

Sara Pourshahidi (1)

Shiva Shirazian (1)

Style	Citing Format
MLA	Kazemian H, et al.. "In Vivo Antibacterial and Wound Healing Activities of Roman Chamomile (Chamaemelum Nobile)." Infectious Disorders - Drug Targets, vol. 18, no. 1, 2018, pp. 41-45.
APA	Kazemian H, Ghafourian S, Sadeghifard N, Houshmandfar R, Badakhsh B, Taji A, Shavalipour A, Mohebi R, Ebrahimsaraie HS, Houri H, Heidari H (2018). In Vivo Antibacterial and Wound Healing Activities of Roman Chamomile (Chamaemelum Nobile). Infectious Disorders - Drug Targets, 18(1), 41-45.
Chicago	Kazemian H, Ghafourian S, Sadeghifard N, Houshmandfar R, Badakhsh B, Taji A, Shavalipour A, et al.. "In Vivo Antibacterial and Wound Healing Activities of Roman Chamomile (Chamaemelum Nobile)." Infectious Disorders - Drug Targets 18, no. 1 (2018): 41-45.
Harvard	Kazemian H et al. (2018) 'In Vivo Antibacterial and Wound Healing Activities of Roman Chamomile (Chamaemelum Nobile)', Infectious Disorders - Drug Targets, 18(1), pp. 41-45.
Vancouver	Kazemian H, Ghafourian S, Sadeghifard N, Houshmandfar R, Badakhsh B, Taji A, et al.. In Vivo Antibacterial and Wound Healing Activities of Roman Chamomile (Chamaemelum Nobile). Infectious Disorders - Drug Targets. 2018;18(1):41-45.
BibTex	@article{ author = {Kazemian H and Ghafourian S and Sadeghifard N and Houshmandfar R and Badakhsh B and Taji A and Shavalipour A and Mohebi R and Ebrahimsaraie HS and Houri H and Heidari H}, title = {In Vivo Antibacterial and Wound Healing Activities of Roman Chamomile (Chamaemelum Nobile)}, journal = {Infectious Disorders - Drug Targets}, volume = {18}, number = {1}, pages = {41-45}, year = {2018} }
RIS	TY - JOUR AU - Kazemian H AU - Ghafourian S AU - Sadeghifard N AU - Houshmandfar R AU - Badakhsh B AU - Taji A AU - Shavalipour A AU - Mohebi R AU - Ebrahimsaraie HS AU - Houri H AU - Heidari H TI - In Vivo Antibacterial and Wound Healing Activities of Roman Chamomile (Chamaemelum Nobile) JO - Infectious Disorders - Drug Targets VL - 18 IS - 1 SP - 41 EP - 45 PY - 2018 ER -

Science Communicator Platform

Authors

Authors Affiliations

Abstract