Expression Analysis of Apoptosis-Related Genes in Bladder Cancer Patients

Expression Analysis of Apoptosis-Related Genes in Bladder Cancer Patients Publisher

Yazarlou F¹ ; Afsharpad M² ; Oskooei VK³ ; Nekoohesh L⁴ ; Moharrami T⁵ ; Samadaian N¹ ; Ghafourifard S³ ; Modarressi MH^{1, 6}

Source: Meta Gene Published:2018

Abstract

Background: Bladder cancer (BC) is a frequent cancer with high morbidity and mortality. Method: We assessed expression of NMP22, BAG3, BCL2 and BAX in BC samples, adjacent non-neoplastic tissues (ANNTs), urinary cell pellets (UCP) of the same patients and non-malignant conditions (NM). Results: NMP22 was up-regulated in tumoral tissues compared with ANNTs and in UCP of BC patients compared with UCP of NM. BCL2 and BAX were down-regulated in BC tissues compared with ANNTs. BAG3 and BAX were down-regulated in UCP of BC compared with NM. The combination of all four genes had 100% sensitivity and specificity for detection of BC in urine. Conclusion: Expression analysis of these genes in tumor or urine is a tool for detection of BC. © 2018

2. Competing Endogenous Rna (Cerna) Cross Talk and Language in Cerna Regulatory Networks: A New Look at Hallmarks of Breast Cancer, Journal of Cellular Physiology (2019)

3. Urinary Tert Promoter Mutations Are Detectable up to 10 Years Prior to Clinical Diagnosis of Bladder Cancer: Evidence From the Golestan Cohort Study, EBioMedicine (2020)

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Hossein Poustchi (1)

Kazem Zendehdel (1)

Style	Citing Format
MLA	Yazarlou F, et al.. "Expression Analysis of Apoptosis-Related Genes in Bladder Cancer Patients." Meta Gene, vol. 18, no. , 2018, pp. 137-142.
APA	Yazarlou F, Afsharpad M, Oskooei VK, Nekoohesh L, Moharrami T, Samadaian N, Ghafourifard S, Modarressi MH (2018). Expression Analysis of Apoptosis-Related Genes in Bladder Cancer Patients. Meta Gene, 18(), 137-142.
Chicago	Yazarlou F, Afsharpad M, Oskooei VK, Nekoohesh L, Moharrami T, Samadaian N, Ghafourifard S, Modarressi MH. "Expression Analysis of Apoptosis-Related Genes in Bladder Cancer Patients." Meta Gene 18, no. (2018): 137-142.
Harvard	Yazarlou F et al. (2018) 'Expression Analysis of Apoptosis-Related Genes in Bladder Cancer Patients', Meta Gene, 18(), pp. 137-142.
Vancouver	Yazarlou F, Afsharpad M, Oskooei VK, Nekoohesh L, Moharrami T, Samadaian N, et al.. Expression Analysis of Apoptosis-Related Genes in Bladder Cancer Patients. Meta Gene. 2018;18():137-142.
BibTex	@article{ author = {Yazarlou F and Afsharpad M and Oskooei VK and Nekoohesh L and Moharrami T and Samadaian N and Ghafourifard S and Modarressi MH}, title = {Expression Analysis of Apoptosis-Related Genes in Bladder Cancer Patients}, journal = {Meta Gene}, volume = {18}, number = {}, pages = {137-142}, year = {2018} }
RIS	TY - JOUR AU - Yazarlou F AU - Afsharpad M AU - Oskooei VK AU - Nekoohesh L AU - Moharrami T AU - Samadaian N AU - Ghafourifard S AU - Modarressi MH TI - Expression Analysis of Apoptosis-Related Genes in Bladder Cancer Patients JO - Meta Gene VL - 18 IS - SP - 137 EP - 142 PY - 2018 ER -

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