Predictive Accuracy of 24-Hour Ambulatory Blood Pressure Monitoring Versus Clinic Blood Pressure for Cardiovascular and All-Cause Mortality: A Systematic Review and Meta-Analysis Publisher Pubmed



H Soleimani HAMIDREZA ; Nsh Mohammadi Negin Sadat HOSSEINI ; Sm Namin Sara MONTAZERI ; A Nasrollahizadeh AMIR ; T Azardar TARA ; K Najafi KIMIA ; M Cilingiroglu MEHMET ; Ma Syed Mushabbar A ; Mk Askari Mani KHORSAND ; R Gupta RAHUL
Source: Current Hypertension Reviews Published:2025

Abstract

Introduction: According to current clinical practice guidelines, Ambulatory Blood Pressure Measurement (ABPM) is recommended to confirm diagnoses of hypertension. It remains unclear as to which method is superior in predicting mortality outcomes. Methods: Prospective observational studies, comparing ABPM with Clinical Blood Pressure Measurements (CBPM), were included with outcomes of the study being all-cause and cardiovascular mortality. Results: Nine studies with a total of 23,140 participants were included. Each 10-mmHg increase in 24-hour mean systolic blood pressure (SBP) was linked to a higher risk of all-cause mortality (HR: 1.13, 95% CI: 1.09–1.18), while Clinic Blood Pressure Measurement (CBPM) was not a significant predictor (HR: 1.02, 95% CI: 0.90–1.13). Nighttime SBP increases of 10 mmHg were associated with a higher all-cause mortality risk than daytime SBP (HR: 1.16, 95% CI: 1.11–1.21 versus HR: 1.08, 95% CI: 1.05–1.12). For cardiovascular mortality, a 10 mmHg increase in SBP yielded an HR of 1.21 (95% CI: 1.16–1.27) for 24-hour ABPM compared to 1.08 (95% CI: 1.04–1.11) for CBPM. Similarly, for a 5 mmHg increase in Diastolic Blood Pressure (DBP), the HR was 1.14 (95% CI: 1.07–1.20) for 24 hour ABPM versus 1.04 (95% CI: 1.01–1.07) for clinical DBP, highlighting 24-hour monitoring as a stronger predictor for cardiovascular mortality. Conclusion: The findings of this study support the superiority of ABPM measurements in predicting both all-cause and cardiovascular mortality. © 2025 Elsevier B.V., All rights reserved.