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A Comprehensive Review of Behcet's Disease Damage Assessment Tools Publisher



Khabbazi A1 ; Mehrtabar E2 ; Mehrtabar S3 ; Khalaji A1 ; Malek Mahdavi A4
Authors
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Authors Affiliations
  1. 1. Connective Tissue Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
  2. 2. Advanced Diagnostic and Interventional Radiology Research Center, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
  4. 4. Tuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

Source: Archives of Medical Research Published:2025


Abstract

Outcome assessment of rheumatic diseases has a significant role in evaluating the effect of various therapies in clinical studies and in the treatment of these patients in daily practice. Outcome assessment in rheumatic disorders is based on the evaluation of disease activity, quality of life, disability, and mortality caused by the disease. Behcet's disease (BD) is a multisystem inflammatory condition that can cause damage to multiple organs. Damage assessment, along with assessment of BD activity, are two necessary and complementary components of BD outcome measures, based on Outcome Measures in Rheumatology. In clinical trials of BD, outcome assessment has been based on disease activity measures, which do not measure damage severity. In this review, we considered three damage indices that have recently been introduced to assess BD-related injury, including vasculitis damage index (VDI), Behcet's syndrome overall damage index (BODI), and Behcet's disease damage index (BDI). © 2025 Instituto Mexicano del Seguro Social (IMSS)
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1. Association of Lifestyle Elements With Self-Rated Wellness and Health Status in Patients With Behcet's Disease, BMC Rheumatology (2020)