A Prospective Study of Laboratory Findings in Dapsone Treated Patients With Pemphigus Vulgaris and Foliaceus

A Prospective Study of Laboratory Findings in Dapsone Treated Patients With Pemphigus Vulgaris and Foliaceus

Afrasiabi M¹ ; Esmaeilinejad S² ; Asgary V³ ; Cohan RA⁴ ; Naji T¹ ; Seirafi H⁵ ; Bigdeli R⁶ ; Mohamadi S⁷

Show Affiliations

1. Pharmaceutical Sciences Branch, Islamic Azad University, Tehran, Iran
2. Department of Public Biology, East Tehran Branch of Payam_e_Noor University, Tehran, Iran
3. Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
4. Department of Pilot Nano-biotechnology, New Technologies Research Group, Pasteur Institute of Iran, Tehran, Iran
5. Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran
6. Research and Development Laboratory, Javid Biotechnology Company, Incubator of Pasteur Institute of Iran, Tehran, Iran
7. Central Laboratory, Ayatollah Taleghani Hospital, Tehran, Iran

Source: Biomedical Research (India) Published:2017

Abstract

Background: Pemphigus is an autoimmune disorder of skin and mucous membranes that appears in the form of blistering on skin and mucous membrane and may lead to loss of life in the absence of proper treatment. Treatment is effected by using immunosuppressant drugs such as Azathioprine cyclophosphamide and some others. Objective: Our purpose of this study was to survey about blood, hepatic and renal side effects of dapsone with the patients affected by Pemphigus. Methods: The test was carried out on 37 patients who were suffering from acute Pemphigus and had undergone some therapy with dapsone amongst which 5 patients were excluded from the research because of hepatic and hematic symptoms. The study was carried on with 31 patients with an average age of 40 ± 17.5. They had no symptoms necessitating the stop of administration of the medicine. Results: Statistical analysis indicated no significant difference in the test results before and after the therapy and only platelet counts showed significant difference before and after the therapy (p<0.05). Conclusion: This study indicated that among all disagreements about dapsone treatment, dapsone can be applied as adjuvant therapy. © 2017, Scientific Publishers of India. All rights reserved.

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Style	Citing Format
MLA	Afrasiabi M, et al.. "A Prospective Study of Laboratory Findings in Dapsone Treated Patients With Pemphigus Vulgaris and Foliaceus." Biomedical Research (India), vol. 28, no. 3, 2017, pp. 1066-1069.
APA	Afrasiabi M, Esmaeilinejad S, Asgary V, Cohan RA, Naji T, Seirafi H, Bigdeli R, Mohamadi S (2017). A Prospective Study of Laboratory Findings in Dapsone Treated Patients With Pemphigus Vulgaris and Foliaceus. Biomedical Research (India), 28(3), 1066-1069.
Chicago	Afrasiabi M, Esmaeilinejad S, Asgary V, Cohan RA, Naji T, Seirafi H, Bigdeli R, Mohamadi S. "A Prospective Study of Laboratory Findings in Dapsone Treated Patients With Pemphigus Vulgaris and Foliaceus." Biomedical Research (India) 28, no. 3 (2017): 1066-1069.
Harvard	Afrasiabi M et al. (2017) 'A Prospective Study of Laboratory Findings in Dapsone Treated Patients With Pemphigus Vulgaris and Foliaceus', Biomedical Research (India), 28(3), pp. 1066-1069.
Vancouver	Afrasiabi M, Esmaeilinejad S, Asgary V, Cohan RA, Naji T, Seirafi H, et al.. A Prospective Study of Laboratory Findings in Dapsone Treated Patients With Pemphigus Vulgaris and Foliaceus. Biomedical Research (India). 2017;28(3):1066-1069.
BibTex	@article{ author = {Afrasiabi M and Esmaeilinejad S and Asgary V and Cohan RA and Naji T and Seirafi H and Bigdeli R and Mohamadi S}, title = {A Prospective Study of Laboratory Findings in Dapsone Treated Patients With Pemphigus Vulgaris and Foliaceus}, journal = {Biomedical Research (India)}, volume = {28}, number = {3}, pages = {1066-1069}, year = {2017} }
RIS	TY - JOUR AU - Afrasiabi M AU - Esmaeilinejad S AU - Asgary V AU - Cohan RA AU - Naji T AU - Seirafi H AU - Bigdeli R AU - Mohamadi S TI - A Prospective Study of Laboratory Findings in Dapsone Treated Patients With Pemphigus Vulgaris and Foliaceus JO - Biomedical Research (India) VL - 28 IS - 3 SP - 1066 EP - 1069 PY - 2017 ER -

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