Traffic Noise Exposure Increases Gastric Pepsin Secretion in Rat

Traffic Noise Exposure Increases Gastric Pepsin Secretion in Rat Pubmed

Moslehi A¹ ; Nabavizadeh F² ; Keshavarz M² ; Rouhbakhsh N³ ; Sotudeh M⁴ ; Salimi E⁵ ; Behrooz AB²

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1. Department of Physiology and Pharmacology, School of Medicine, Qom University of Medical Sciences, Qom, Iran
2. Department of Physiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
3. Department of Audiology, Tehran University of Medical Sciences, Tehran, Iran
4. Department of Pathology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
5. Department of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran

Source: Acta Medica Iranica Published:2016

Abstract

Noise is considered as one of the most severe sources of environmental and workplace constraints. Many noise effects are well known on immune function, hormonal levels, cardiovascular and respiratory systems. In this study, our aim is to evaluate the effects of traffic noise exposure on basal and stimulated gastric pepsin secretion. 48 male rats were exposed to traffic noise (86 dB) for a short term of (8h/ day for 1 day) and a long term of (8h/ day for 7, 14, 21 and 28 days) as well as a control group. The gastric contents were collected by the wash-out technique. Pepsin secretion was measured by employing the Anson method. Histological studies were carried out on the epithelial layer. The corticosteroid hormone was measured in the serum for the stress augmentation. The present finding indicated no changes in pepsin secretion content in the short term, but in the 14 and 21 days traffic noise exposure, basal gastric pepsin secretion increased markedly compared to the control group. Histological results showed that the number of oxyntic glands and cell nuclei decreased in comparison with the control group while the thickness of the epithelial layer increases. In addition, the corticosterone levels increase in all groups in comparison with the control. It seems that the increase of gastric pepsin secretion is due to the description and translation processes in the peptic cells and needs enough time for completion. © 2016 Tehran University of Medical Sciences. All rights reserved..

Style	Citing Format
MLA	Moslehi A, et al.. "Traffic Noise Exposure Increases Gastric Pepsin Secretion in Rat." Acta Medica Iranica, vol. 54, no. 3, 2016, pp. 191-195.
APA	Moslehi A, Nabavizadeh F, Keshavarz M, Rouhbakhsh N, Sotudeh M, Salimi E, Behrooz AB (2016). Traffic Noise Exposure Increases Gastric Pepsin Secretion in Rat. Acta Medica Iranica, 54(3), 191-195.
Chicago	Moslehi A, Nabavizadeh F, Keshavarz M, Rouhbakhsh N, Sotudeh M, Salimi E, Behrooz AB. "Traffic Noise Exposure Increases Gastric Pepsin Secretion in Rat." Acta Medica Iranica 54, no. 3 (2016): 191-195.
Harvard	Moslehi A et al. (2016) 'Traffic Noise Exposure Increases Gastric Pepsin Secretion in Rat', Acta Medica Iranica, 54(3), pp. 191-195.
Vancouver	Moslehi A, Nabavizadeh F, Keshavarz M, Rouhbakhsh N, Sotudeh M, Salimi E, et al.. Traffic Noise Exposure Increases Gastric Pepsin Secretion in Rat. Acta Medica Iranica. 2016;54(3):191-195.
BibTex	@article{ author = {Moslehi A and Nabavizadeh F and Keshavarz M and Rouhbakhsh N and Sotudeh M and Salimi E and Behrooz AB}, title = {Traffic Noise Exposure Increases Gastric Pepsin Secretion in Rat}, journal = {Acta Medica Iranica}, volume = {54}, number = {3}, pages = {191-195}, year = {2016} }
RIS	TY - JOUR AU - Moslehi A AU - Nabavizadeh F AU - Keshavarz M AU - Rouhbakhsh N AU - Sotudeh M AU - Salimi E AU - Behrooz AB TI - Traffic Noise Exposure Increases Gastric Pepsin Secretion in Rat JO - Acta Medica Iranica VL - 54 IS - 3 SP - 191 EP - 195 PY - 2016 ER -

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