Electrospun Poly(Ε-Caprolactone)/Gelatin Nanofibrous Mat Containing Selenium As a Potential Wound Dressing Material: In Vitro and in Vivo Study

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Electrospun Poly(Ε-Caprolactone)/Gelatin Nanofibrous Mat Containing Selenium As a Potential Wound Dressing Material: In Vitro and in Vivo Study Publisher

Salehi M^{1, 2, 3} ; Shahporzadeh K³ ; Ehterami A⁴ ; Yeganehfard H³ ; Ziaei H³ ; Azizi MM³ ; Farzamfar S⁵ ; Tahersoltani A³ ; Goodarzi A⁷ ; Ai J^{5, 6} ; Ahmadi A⁵

Source: Fibers and Polymers Published:2020

Abstract

In the current study, selenium particles were loaded into poly(ε-caprolactone)/gelatin nanofibrous matrices in order to fabricate a potential wound dressing. The mats were produced by electrospinning of poly(ε-caprolactone)/Gelatin (1:1 (w/w)) solution supplemented with 1 and 10 % (w/v) of selenium particles. Prepared wound dressings were investigated regarding their morphology, mechanical properties, surface wettability, water-uptake capacity, water vapor permeability, porosity, blood compatibility, microbial penetration test and cellular response. Dressings containing 1 % and 10 % selenium and selenium free mats were chosen to treat the full-thickness excisional wounds in Wistar rats. The study revealed that after 14 days, the wound closure of the mat containing 1 % selenium was about 95.5±6.38 % while wound closure of the negative control group was about 48.83±4.03 %. Our results showed the capability of nanofibrous containing selenium for successful wound treatment. © 2020, The Korean Fiber Society.

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Style	Citing Format
MLA	Salehi M, et al.. "Electrospun Poly(Ε-Caprolactone)/Gelatin Nanofibrous Mat Containing Selenium As a Potential Wound Dressing Material: In Vitro and in Vivo Study." Fibers and Polymers, vol. 21, no. 8, 2020, pp. 1713-1721.
APA	Salehi M, Shahporzadeh K, Ehterami A, Yeganehfard H, Ziaei H, Azizi MM, Farzamfar S, Tahersoltani A, Goodarzi A, Ai J, Ahmadi A (2020). Electrospun Poly(Ε-Caprolactone)/Gelatin Nanofibrous Mat Containing Selenium As a Potential Wound Dressing Material: In Vitro and in Vivo Study. Fibers and Polymers, 21(8), 1713-1721.
Chicago	Salehi M, Shahporzadeh K, Ehterami A, Yeganehfard H, Ziaei H, Azizi MM, Farzamfar S, et al.. "Electrospun Poly(Ε-Caprolactone)/Gelatin Nanofibrous Mat Containing Selenium As a Potential Wound Dressing Material: In Vitro and in Vivo Study." Fibers and Polymers 21, no. 8 (2020): 1713-1721.
Harvard	Salehi M et al. (2020) 'Electrospun Poly(Ε-Caprolactone)/Gelatin Nanofibrous Mat Containing Selenium As a Potential Wound Dressing Material: In Vitro and in Vivo Study', Fibers and Polymers, 21(8), pp. 1713-1721.
Vancouver	Salehi M, Shahporzadeh K, Ehterami A, Yeganehfard H, Ziaei H, Azizi MM, et al.. Electrospun Poly(Ε-Caprolactone)/Gelatin Nanofibrous Mat Containing Selenium As a Potential Wound Dressing Material: In Vitro and in Vivo Study. Fibers and Polymers. 2020;21(8):1713-1721.
BibTex	@article{ author = {Salehi M and Shahporzadeh K and Ehterami A and Yeganehfard H and Ziaei H and Azizi MM and Farzamfar S and Tahersoltani A and Goodarzi A and Ai J and Ahmadi A}, title = {Electrospun Poly(Ε-Caprolactone)/Gelatin Nanofibrous Mat Containing Selenium As a Potential Wound Dressing Material: In Vitro and in Vivo Study}, journal = {Fibers and Polymers}, volume = {21}, number = {8}, pages = {1713-1721}, year = {2020} }
RIS	TY - JOUR AU - Salehi M AU - Shahporzadeh K AU - Ehterami A AU - Yeganehfard H AU - Ziaei H AU - Azizi MM AU - Farzamfar S AU - Tahersoltani A AU - Goodarzi A AU - Ai J AU - Ahmadi A TI - Electrospun Poly(Ε-Caprolactone)/Gelatin Nanofibrous Mat Containing Selenium As a Potential Wound Dressing Material: In Vitro and in Vivo Study JO - Fibers and Polymers VL - 21 IS - 8 SP - 1713 EP - 1721 PY - 2020 ER -

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