Mucormycosis Mimicking Tracheal Tumor: A Case Report; [موکورمایکوزیس مقلد تومور تراشه: گزارش موردي] Publisher



Ansari R¹ ; Dabirmoghaddam P¹ ; Lotfi M² ; Gheitani M³ ; Sohrabpour S¹ ; Heidari F¹ Show Affiliations
Source: Iranian Journal of Medical Microbiology Published:2021

Abstract

complaining of shortness of breath which had lasted for three weeks. Due to inspiratory and expiratory stridor in the clinical examination, a tracheal lesion was proposed for her. In computed tomography (CT) scan (without contrast) of the neck and chest, a lesion resembling a malignant tracheal tumor was observed spreading around the cervical trachea. Subsequently, the patientchr('39')s respiratory distress worsened and she underwent tracheostomy under general anesthesia. During tracheostomy, a white to creamy lesion that resembled necrosis with extensive granulation was seen in cervical trachea, and a biopsy was taken. Histopathological reports showed evidence of acute and chronic inflammation, in necrotic background, along with aseptate fungi which confirmed mucormycosis. Initially, intravenous liposomal amphotericin-B was selected as an antifungal drug which was discontinued due to drug-induced acute renal failure. Posaconazole suspension was replaced as an antifungal drug. After about six weeks, the patient was discharged from the hospital in good general condition. Contrary to few previous studies on mucormycosis of the trachea and lower airways, tracheal disease was limited in our patient; therefore, we avoided debridement of the conflict site and tried to control the disease by controlling the underlying disease (DM), and antifungal therapy. Finally, the desired result was achieved. It should be noted that all patients who have been reviewed in the previous published studies have had a wider conflict sites compared to our patient. Therefore, due to the lack of standard treatment for this disease, our therapeutic approach in this study can be considered as an option in limited and localized cases. © 2021, This is an original open-access article distributed under the terms of the Creative Commons Attribution-noncommercial 4.0 International License which permits copy and redistribution of the material just in noncommercial usages with proper citation.