Subglottic Mucormycosis in a Covid-19 Patient: A Rare Case Report Publisher



Amirzargar B¹ ; Jafari M¹ ; Ahmadinejad Z² ; Salehi M² ; Chalabi S² ; Aminishakib P³ ; Salahshoor F⁴ ; Khodavaisy S⁵ ; Zabihidan M¹ Show Affiliations
Source: Oxford Medical Case Reports Published:2022

Abstract

Mucormycosis is an opportunistic fungal infection caused by fungi of Mucorale order. Uncontrolled diabetes mellitus and other immunosuppressive conditions such as neutropenia and corticosteroid therapy are known risk factors. A new risk factor for this infection is COVID-19 which facilitates mucormycosis by different mechanisms. The rhino-orbito-cerebral involvement is the most common form. Involvement of other anatomical regions may occur in rare situations. As we presented here, a 51-year-old woman presented with respiratory distress and subglottic lesion during COVID-19 (Delta variant) treatment which was diagnosed by histopathological examination as a subglottic mucormycosis postoperatively. The patient underwent tracheostomy and debridement of the necrotic tissues followed by antifungal treatment. New manifestations of COVID-19 are appearing over time. The association between coronavirus and mucormycosis of the laryngeal and airway region must be given serious consideration. Current guidelines recommend a combined medical and surgical approach for achieving the best outcome. © 2022 The Author(s). Published by Oxford University Press. All rights reserved.