Tehran University of Medical Sciences

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Hsv-2 Induced Cerebellitis: A Case Report of Hsv-2 Reactivation by Sars-Cov-2 Infection Publisher



Ehsanipur F1 ; Vafaeeshahi M2 ; Tahernia L3 ; Riahi A4
Authors
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Authors Affiliations
  1. 1. Department of Pediatric Infectious Diseases, Rasool Akram Hospital, Iran University of Medical Sciences, Tehran, Iran
  2. 2. Pediatric Growth and Development Research center, Iran University of Medical Sciences, Tehran, Iran
  3. 3. Pediatric Intensive Care Unit, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Ali-asghar Children Hospital, Iran University of Medical Sciences, Tehran, Iran

Source: Open Neurology Journal Published:2023


Abstract

Herpes simplex virus type 2 rarely causes encephalitis in humans. Some DNA viruses, such as HSV-1 and HSV-2, can be reactivated by COVID-19 infection. SARS-CoV-2 causes a wide spectrum of neurological deficits, such as stroke, delirium, movement disorders, and neuropathy. An unusual manifestation of HSV-2 was diagnosed as cerebellitis in our patient. It was concluded that SARS-CoV-2 can reactivate DNA viruses, such as HSV-2. Here, we reported a 1-year-old female infant with cerebellitis due to herpes simplex virus type 2 infection. The patient was treated with intravenous acyclovir and oral prednisolone for three weeks. Finally, during her 9-month neurological follow-up, she was able to walk with minimal ataxia. © 2023 The Author(s).