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Hsv-1 Infection Among Covid-19 Cases With Ocular and Neurological Manifestations Publisher



Soltani S1 ; Sadrkhanloo M2 ; Siri G3 ; Zakeri AM4 ; Emadi MS5 ; Tabibzadeh A6 ; Didehdar M7 ; Farahani A8, 9
Authors
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Authors Affiliations
  1. 1. Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Faculty of Medicine, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran
  3. 3. Department of Internal Medicine, Amir Alam Hospital, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Pediatric Surgery Research Center, Research Institute for Children’s Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  5. 5. Department of Medical Laboratory Sciences, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Department of Virology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
  7. 7. Department of Medical Parasitology and Mycology, Arak University of Medical Sciences, Arak, Iran
  8. 8. Department of Medical Laboratory Sciences, Khomein University of Medical Sciences, Khomein, Iran
  9. 9. Molecular and Medicine Research Center, Khomein University of Medical Sciences, Khomein, Iran

Source: Jundishapur Journal of Microbiology Published:2023


Abstract

Introduction: SARS-CoV-2 progression depends on multiple factors, including the compromised immune system and underlying diseases. HSV-1 reactivation in SARS-CoV-2 infection, more likely in patients with pneumonia and immunodeficiency, may be poten-tially life-threatening and implicate the prognosis. Case Presentation: We report two COVID-19 cases presenting ocular and neurological manifestations suspicious for HSV-1 en-cephalitis. Conclusions: Our study showed HSV-1 ocular manifestation among two COVID-19 cases. So, the recurrence of HSV-1 infection prob-ably is related to immune responses during COVID-19 pathophysiology. © 2023, Author(s).