Early Onset Hepatocellular Disease in an Infant With Zellweger Syndrome

Early Onset Hepatocellular Disease in an Infant With Zellweger Syndrome Pubmed

Sani MN¹ ; Ahmadi M¹ ; Roohani P¹ ; Rezaei N^{2, 3, 4}

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1. Department of Pediatric Gastroenterology, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran
2. Research Center for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran
3. Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
4. Universal Scientific Education and Research Network (USERN), Tehran, Iran

Source: Acta Medica Iranica Published:2015

Abstract

Zellweger syndrome (ZS) is a peroxisomal disorder with a multiple congenital anomalies, characterized by stereotypical facies, profound hypotonia, organ involvement including cerebral, retinal, hepatic, and renal. Herein, a 3-month-old female with ZS is presented who was referred because of increased liver enzymes (subclinical hepatitis), which was detected in work-up of her neck cyst, severe hypotonia, and abnormal facies. An increased concentration of very long chain fatty acid in lipid profile was detected. ZS should be considered in the list of differential diagnosis in infants with stereotypical phenotype, neurodevelopmental delay, and severe hypotonia in association with liver and other organs involvement. © 2015 Tehran University of Medical Sciences. All rights reserved.

Style	Citing Format
MLA	Sani MN, et al.. "Early Onset Hepatocellular Disease in an Infant With Zellweger Syndrome." Acta Medica Iranica, vol. 53, no. 10, 2015, pp. 656-658.
APA	Sani MN, Ahmadi M, Roohani P, Rezaei N (2015). Early Onset Hepatocellular Disease in an Infant With Zellweger Syndrome. Acta Medica Iranica, 53(10), 656-658.
Chicago	Sani MN, Ahmadi M, Roohani P, Rezaei N. "Early Onset Hepatocellular Disease in an Infant With Zellweger Syndrome." Acta Medica Iranica 53, no. 10 (2015): 656-658.
Harvard	Sani MN et al. (2015) 'Early Onset Hepatocellular Disease in an Infant With Zellweger Syndrome', Acta Medica Iranica, 53(10), pp. 656-658.
Vancouver	Sani MN, Ahmadi M, Roohani P, Rezaei N. Early Onset Hepatocellular Disease in an Infant With Zellweger Syndrome. Acta Medica Iranica. 2015;53(10):656-658.
BibTex	@article{ author = {Sani MN and Ahmadi M and Roohani P and Rezaei N}, title = {Early Onset Hepatocellular Disease in an Infant With Zellweger Syndrome}, journal = {Acta Medica Iranica}, volume = {53}, number = {10}, pages = {656-658}, year = {2015} }
RIS	TY - JOUR AU - Sani MN AU - Ahmadi M AU - Roohani P AU - Rezaei N TI - Early Onset Hepatocellular Disease in an Infant With Zellweger Syndrome JO - Acta Medica Iranica VL - 53 IS - 10 SP - 656 EP - 658 PY - 2015 ER -

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