Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Reactions Involving Multiple Isocyanide Insertions Publisher



Tashrifi Z1 ; Mohammadi Khanaposhtani M2 ; Gholami F1 ; Larijani B1 ; Mahdavi M1
Authors
Show Affiliations
Authors Affiliations
  1. 1. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Faculty of Fouman, College of Engineering, University of, Fouman, Tehran, Iran

Source: Advanced Synthesis and Catalysis Published:2023


Abstract

Isocyanides (isonitriles or carbylamine) have been intensively used in organic synthesis to prepare a diverse variety of N-heterocycles on the basis of the carbene-like reactivity of their divalent carbon atom. Isocyanides participate in a variety of reactions involving one, two, or more isocyanides. Compared to the popularity of single isocyanide reactions, few examples of reactions involving two or more isocyanides have been reported. In this review, we categorized and classified the literatures of reactions involving two or more isocyanides especially double isocyanide insertions under metal-catalyzed or metal-free conditions from 2014 to 2022. (Figure presented.). © 2023 Wiley-VCH GmbH.