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Silver and Copper-Catalyzed Cycloaddition Reactions of Isocyanide Esters Publisher



Doraghi F1 ; Baghershahi P2 ; Gilaninezhad F3 ; Darban NMZ4 ; Dastyafteh N1 ; Noori M1 ; Mahdavi M1
Authors
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Authors Affiliations
  1. 1. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Pharmaceutical and Heterocyclic Chemistry Research Laboratory, Department of Chemistry, Iran University of Science and Technology, Tehran, Iran
  3. 3. School of Chemistry, College of Science, University of Tehran, Tehran, Iran
  4. 4. College of Chemistry, Khaje Nasir Toosi University of Technology, Tehran, Iran

Source: Advanced Synthesis and Catalysis Published:2025


Abstract

Owing to multiple reactive sites, such as an acidic α-carbon and an isocyano group, isocyanide esters can successfully participate in the synthesis of various five- and six-membered N-heterocycles through the cycloaddition reactions under metal-catalyzed systems. Considering the unique and versatile functionality of this synthon, in this review, we have highlighted silver and copper-catalyzed cycloadditions of isocyanide esters over the last decade. © 2025 Wiley-VCH GmbH.