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The Role of Ubiquitin-Specific Peptidases in Colorectal Cancer: A Systematic Review Protocol Publisher



Albalushi E1 ; Almarzouqi A1 ; Tavoosi S2, 3 ; Baghsheikhi AH3, 4 ; Sadri A5, 6 ; Aliabadi LS7 ; Salarabedi MM8 ; Rahman SA1 ; Alyateem N1 ; Jarrahi AM9 ; Halimi A10, 11 ; Ahmadvand M7 ; Abdelrahman WM12
Authors
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Authors Affiliations
  1. 1. College of Health Sciences, University of Sharjah, Sharjah, United Arab Emirates
  2. 2. Department of Biology, Faculty of Sciences, University of Isfahan, Hezar Jerib Ave., Azadi Square, Isfahan, 81746-73441, Iran
  3. 3. Department of Cellular and Molecular Biology, Islamic Azad University Tehran Medical Sciences, Tehran, Iran
  4. 4. Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran
  5. 5. Lyceum Scientific Charity, Iran
  6. 6. Students’ Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran
  7. 7. Cell Therapy and Hematopoietic Stem Cell Transplantation Research Center, Research Institute for Oncology, Hematology, and Cell Therapy, Tehran University of Medical Sciences, Tehran, Iran
  8. 8. Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  9. 9. Cancer Research Centre, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  10. 10. Department of Epidemiology, School of Public Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  11. 11. Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  12. 12. Department of Medical Laboratory Sciences, College of Health Sciences and Research Institute of Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates

Source: Asia Pacific Journal of Cancer Biology Published:2023


Abstract

Background: This systematic review aims to comprehensively assess and synthesize the current body of evidence regarding the role of ubiquitin-specific peptidases in colorectal cancer. Methods: This protocol adhered to the guidelines outlined in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocol (PRISMA-P) and was officially registered with the International Prospective Register for Systematic Reviews (PROSPERO) under the registration number CRD42022348183. Results: This study will provide a concise summary of the synthesized data from the included studies and will synthesize key findings, explore clinical and therapeutic implications, address limitations and gaps in knowledge, and propose avenues for future research.Conclusion: This section will conclude by summarizing the key takeaways from the systematic review and emphasizing the relevance of the findings in advancing our knowledge of the role of USPs in colorectal cancer. It will also underscore the potential implications for clinical practice and future research directions. © This work is licensed under a Creative Commons Attribution-Non Commercial 4.0 International License.
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2. Comprehensive Analysis of the Role of Ubiquitin-Specific Peptidases in Colorectal Cancer: A Systematic Review, World Journal of Gastrointestinal Oncology (2024)
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