Does Recombinant Human Erythropoietin Administration in Critically Ill Covid-19 Patients Have Miraculous Therapeutic Effects?

Does Recombinant Human Erythropoietin Administration in Critically Ill Covid-19 Patients Have Miraculous Therapeutic Effects? Publisher Pubmed

Hadadi A¹ ; Mortezazadeh M² ; Kolahdouzan K³ ; Alavian G⁴

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1. Department of Infectious Diseases, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran
2. Internal Medicine Department, Tehran University of Medical Sciences, Tehran, Iran
3. Radiation Oncology Department, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
4. Pharmacotherapy Department, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of Medical Virology Published:2020

Abstract

An 80-year-old man with multiple comorbidities presented to the emergency department with tachypnea, tachycardia, fever, and critically low O2 saturation and definitive chest computerized tomography scan findings in favor of COVID-19 and positive PCR results in 48 hours. He received antiviral treatment plus recombinant human erythropoietin (rhEPO) due to his severe anemia. After 7 days of treatment, he was discharged with miraculous improvement in his symptoms and hemoglobin level. We concluded that rhEPO could attenuate respiratory distress syndrome and confront the severe acute respiratory syndrome coronavirus 2 virus through multiple mechanisms including cytokine modulation, antiapoptotic effects, leukocyte release from bone marrow, and iron redistribution away from the intracellular virus. © 2020 Wiley Periodicals, Inc.

Style	Citing Format
MLA	Hadadi A, et al.. "Does Recombinant Human Erythropoietin Administration in Critically Ill Covid-19 Patients Have Miraculous Therapeutic Effects?." Journal of Medical Virology, vol. 92, no. 7, 2020, pp. 915-918.
APA	Hadadi A, Mortezazadeh M, Kolahdouzan K, Alavian G (2020). Does Recombinant Human Erythropoietin Administration in Critically Ill Covid-19 Patients Have Miraculous Therapeutic Effects?. Journal of Medical Virology, 92(7), 915-918.
Chicago	Hadadi A, Mortezazadeh M, Kolahdouzan K, Alavian G. "Does Recombinant Human Erythropoietin Administration in Critically Ill Covid-19 Patients Have Miraculous Therapeutic Effects?." Journal of Medical Virology 92, no. 7 (2020): 915-918.
Harvard	Hadadi A et al. (2020) 'Does Recombinant Human Erythropoietin Administration in Critically Ill Covid-19 Patients Have Miraculous Therapeutic Effects?', Journal of Medical Virology, 92(7), pp. 915-918.
Vancouver	Hadadi A, Mortezazadeh M, Kolahdouzan K, Alavian G. Does Recombinant Human Erythropoietin Administration in Critically Ill Covid-19 Patients Have Miraculous Therapeutic Effects?. Journal of Medical Virology. 2020;92(7):915-918.
BibTex	@article{ author = {Hadadi A and Mortezazadeh M and Kolahdouzan K and Alavian G}, title = {Does Recombinant Human Erythropoietin Administration in Critically Ill Covid-19 Patients Have Miraculous Therapeutic Effects?}, journal = {Journal of Medical Virology}, volume = {92}, number = {7}, pages = {915-918}, year = {2020} }
RIS	TY - JOUR AU - Hadadi A AU - Mortezazadeh M AU - Kolahdouzan K AU - Alavian G TI - Does Recombinant Human Erythropoietin Administration in Critically Ill Covid-19 Patients Have Miraculous Therapeutic Effects? JO - Journal of Medical Virology VL - 92 IS - 7 SP - 915 EP - 918 PY - 2020 ER -

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