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Current Evidence Regarding Alternative Techniques for Enterocystoplasty Using Regenerative Medicine Methods: A Systematic Review Publisher Pubmed



Arabzadeh Bahri R1, 2 ; Peisepar M2, 3 ; Maleki S4 ; Esmaeilpur Abianeh F2, 3 ; A Basti F5 ; Kolahdooz A6
Authors
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Authors Affiliations
  1. 1. Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Universal Scientific Education and Research Network (USERN), Tehran, Iran
  3. 3. School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
  5. 5. Tehran Medical Branch, Islamic Azad University, Tehran, Iran
  6. 6. Student Research Committee, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran

Source: European Journal of Medical Research Published:2024


Abstract

Enterocystoplasty is the most commonly used treatment for bladder reconstruction. However, it has some major complications. In this study, we systematically reviewed the alternative techniques for enterocystoplasty using different scaffolds. A comprehensive search was conducted in PubMed, Embase, and Cochrane Library, and a total of 10 studies were included in this study. Five different scaffolds were evaluated, including small intestinal submucosa (SIS), biodegradable scaffolds seeded with autologous bladder muscle and urothelial cells, dura mater, human cadaveric bladder acellular matrix graft, and bovine pericardium. The overall results revealed that bladder reconstruction using regenerative medicine is an excellent alternative method to enterocystoplasty regarding the improvement of bladder capacity, bladder compliance, and maximum detrusor pressure; however, more large-scale studies are required. © The Author(s) 2024.
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