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Success in Tooth Bud Regeneration: A Short Communication Publisher Pubmed



Sadrabad MJ1, 2 ; Saberian E3 ; Izadi A4 ; Emami R5 ; Ghadyani F6
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Source: Journal of Endodontics Published:2024


Abstract

Introduction: Tooth caries and loss are frequent clinical diseases in dentistry. Tissue engineering is a new therapeutic choice for the complete biological regeneration of pulpal and dental tissues in regenerative dentistry. The aim of this study was to establish a protocol for in situ regeneration of a dental bud in the extracted socket. Methods: The current study examined tooth bud regeneration with dental pulp stem cells induced by a dentin derivative signal in a rabbit's jaw. Result: A tooth bud was regenerated; the morphology and structure of it were typical, and it was post–Bell stage. Conclusions: In our study, a real tooth bud was formed in the post–Bell stage with complete morphologic and biological features. However, the application of this method for tooth regeneration in humans necessitates further research. © 2023 American Association of Endodontists
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