Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
The Epidemiology and Etiology of Onychomycosis in 2 Laboratory Centers Affiliated to Tehran University of Medical Sciences During 2019-2020 Publisher



Razavyoon T1 ; Hashemia SJ1 ; Mansouri P2 ; Rafat Z3 ; Sabooryaraghi AA4 ; Sarvestani HK1 ; Ghasemi Z5
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Medical Parasitology and Mycology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
  4. 4. Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Department of Medical Mycology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran

Source: Iranian Journal of Microbiology Published:2022


Abstract

Background and Objectives: Onychomycosis is caused by dermatophyte species, non-dermatophyte moulds (NDMs), and accounts for roughly 50% of all nail diseases. As the prevalence of onychomycosis is increasing, new epidemiologic documents may help with treatment and prevention. The present investigation aims to determine the epidemiological profile of onychomycosis in 2 mycology laboratories. Materials and Methods: A cross-sectional study conducted during eight months (2019-2020) on 169 patients with positive nail mycology tests referred to two mycological laboratory centers affiliated with Tehran University of Medical Science. The nail clippings were examined by direct smear and culture. Also, molecular assays were performed if needed. Results: 10% of nail lesions referred to Razi Hospital (RH), and 30% of nail lesions referred to TUMS mycology laboratory were positive. Middle age (40-60) suffer more from onychomycosis. Aspergillus flavus, Trichophyton mentagrophytes, and Candida albicans were the most common etiologic agents in each of the three main classes of fungi causing onychomycosis. Females were more infected. NDMs were the predominant etiologic agents, and toenails were the most common site of onychomycosis. Conclusion: The pattern of etiologic agents and clinical signs of onychomycosis differs according to geographical region and age, so repeated epidemiological surveys of onychomycosis seem to be fundamental. © 2022 The Authors. Published by Tehran University of Medical Sciences.
Related Docs
1. A Systematic Review and Meta-Analysis on the Epidemiology, Casual Agents and Demographic Characteristics of Onychomycosis in Iran, Journal de Mycologie Medicale (2019)
2. High Incidence of Onychomycosis Due to Saprophytic Fungi in Yazd, Iran, Iranian Journal of Dermatology (2017)
3. Aspergillus Species As Emerging Causative Agents of Onychomycosis, Journal de Mycologie Medicale (2015)
4. Growing Incidence of Non-Dermatophyte Onychomycosis in Tehran, Iran, Jundishapur Journal of Microbiology (2016)
5. The First Case of Fingernail Onychomycosis Due to Neoscytalidium Novaehollandiae, Molecular Identification and Antifungal Susceptibility, Journal de Mycologie Medicale (2020)
6. Neoscytalidium Dimidiatum As Onychomycosis Causative Agent in an Iranian Patient: A Case Report and Literature Review, New Microbes and New Infections (2022)
Experts (# of related papers)
View all Related Experts
Roshanak Daei Ghazvini (2)
Seyed Jamal Hashemi Hezaveh (2)