Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
The First Case of Total Dystrophic Onychomycosis Caused by Aspergillus Clavatus Resistant to Antifungal Drugs Publisher Pubmed



Falahati M1 ; Ghojoghi A1 ; Abastabar M3 ; Ghasemi Z2 ; Farahyar S1 ; Roudbary M1 ; Hedayati MT3 ; Taghizadeh Armaki M3 ; Hoseinnejad A3
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Medical Mycology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Medical Mycology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Invasive Fungi Research Center (IFRC), Department of Medical Mycology and Parasitology, School of Medicine, Mazandaran University of Medical Sciences, P.O. Box 48175-1665, Sari, Iran

Source: Mycopathologia Published:2016


Abstract

Onychomycosis is a common fungal infection of nails which is mainly caused by dermatophyte species and less often by yeasts and non-dermatophyte molds. We present a case of onychomycosis due to Aspergillus clavatus for the first time worldwide. The patient was an immunocompetent 32-year-old woman who identified with Psoriasis of the nail. The presence of A. clavatus in a nail sample was confirmed using microscopic and culture analysis followed by PCR of the β-tubulin gene. After antifungal susceptibility test, it is revealed that the isolate was resistant to the majority of common antifungal drugs, but finally the patient was treated with itraconazole 200 mg daily. A. clavatus and drug-resistant A. clavatus have not previously been reported from onychomycosis. © 2015, Springer Science+Business Media Dordrecht.
Related Docs
1. Aspergillus Species As Emerging Causative Agents of Onychomycosis, Journal de Mycologie Medicale (2015)
2. Central Nervous System Aspergillus Quadrilineatus Infection in a Covid-19 Patient, a Case Report and Literature Review, Journal of Clinical Laboratory Analysis (2023)