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A Comprehensive, Epidemiological and Ecological Descriptive Study on Vitamin D Status in Iran (308005 People, From 2009-2018)



Farhud DD1, 2, 3 ; Mehrabi A3, 4 ; Sarafnejad A5, 6 ; Sadeghipour HR5, 7 ; Rahimiforoushani A8 ; Rokni MB1 ; Majidi K5 ; Alizadeh A8 ; Zarifyeganeh M3, 9 ; Jalali M5 ; Jalali M5 ; Amir Zargar AA5, 6 ; Khosravi F5, 6 ; Momeni A11 Show All Authors
Authors
  1. Farhud DD1, 2, 3
  2. Mehrabi A3, 4
  3. Sarafnejad A5, 6
  4. Sadeghipour HR5, 7
  5. Rahimiforoushani A8
  6. Rokni MB1
  7. Majidi K5
  8. Alizadeh A8
  9. Zarifyeganeh M3, 9
  10. Jalali M5
  11. Jalali M5
  12. Amir Zargar AA5, 6
  13. Khosravi F5, 6
  14. Momeni A11
  15. Khazeni M5, 12
  16. Hendiani A11
  17. Ahmadi M11
  18. Dehshiri A11
  19. Rasooli P13
Show Affiliations
Authors Affiliations
  1. 1. School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Basic Sciences/Ethics, Iranian Academy of Medical Sciences, Tehran, Iran
  3. 3. Farhud Genetic Clinic, Tehran, Iran
  4. 4. School of Advanced Medical Sciences, Islamic Azad University, Tehran Medical Branch, Tehran, Iran
  5. 5. Noor Pathobiology Laboratory, Tehran, Iran
  6. 6. Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  7. 7. Department of Physiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  8. 8. Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  9. 9. Cellular and Molecular Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  10. 10. Department of Biochemistry, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  11. 11. Booali Pathobiology Laboratory, Qom, Iran
  12. 12. Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  13. 13. Payvand Teb va Narmafzar Company (PTN), Tehran, Iran

Source: Iranian Journal of Public Health Published:2019

Abstract

Background: Vitamin D is an essential substance for absorption of calcium and phosphorus from intestine so it is vital for muscles and skeletal development. Deficiency of this vitamin is pandemic. The vitamin D status depends on the different factors such as UV exposure, diet, and ecological features of living location, age and gender. The aim of this study was to describe the vitamin D level in different provinces of Iran and to investigate the association between vitamin D status and multiple variables. Methods: We collected the serum 25(OH)D (Vitamin D) level data of 308,005 people referred to different laboratories from 30 provinces of Iran and organized them by each province, year, age, gender, precipitation, latitude and longitude, and humidity over 10 yr (2009-2018). Data were analyzed to find out the correlation between age, gender, longitude and latitude, humidity and sum of precipitation. Results: West Azerbaijan had the highest level of vitamin D with a mean level of 33.24 and a standard deviation of 32.001, and North Khorasan had the lowest level with a mean level of 14.46 and a standard deviation of 8.980 among 30 provinces of Iran. The correlation between all studied variables (age, and gender, latitude and longitude, humidity, the sum of precipi-tation) was significant (P<0.001). Conclusion: The average total vitamin D level in Iran is 25.41 ng/ml, which is within the area of deficiency. Vitamin D is associated with age, and gender, latitude and longitude, humidity, the sum of precipitation. So changes in any of these variables can lead to vitamin D alteration. © 2019, Iranian Journal of Public Health. All rights reserved.
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