Iodine Status of Preterm Infants Born in an Area of Iodine Sufficiency: Are They at Risk of Iodine Deficiency?

Iodine Status of Preterm Infants Born in an Area of Iodine Sufficiency: Are They at Risk of Iodine Deficiency? Publisher Pubmed

Nazeri P¹ ; Akbarzadeh M¹ ; Pearce EN² ; Hedayati M³ ; Dalili H¹

Show Affiliations

1. Breastfeeding Research Center, Family Health Research Institute, Tehran University of Medical Sciences, Tehran, Iran
2. Section of Endocrinology, Diabetes and Nutrition, Boston University School of Medicine, Boston, Massachusetts
3. Cellular and Molecular Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Source: Endocrine Practice Published:2022

Abstract

Objective: To the assess the iodine status of preterm infants born in an area of iodine sufficiency using the urinary iodine concentration (UIC) and thyroid-stimulating hormone (TSH) levels and compare these values across different feeding practices during the first 7 days of life. Methods: In this cross-sectional study, 88 preterm infants born at 30 to 34 weeks of gestation and admitted to the neonatal intensive care unit of a referral hospital in Tehran (Iran) were included. The infant UIC and TSH levels and breast milk iodine concentration in mothers who were exclusively breastfeeding were measured. Results: Median (interquartile range [IQR]) UIC and TSH levels in the study population were 81 (39-189) μg/L and 1.60 (0.80-2.85) mIU/L, respectively. When preterm infants were stratified by the type of feeding, the median (IQR) UICs were 64 (42-126) μg/L in parenteral nutrition, 125 (41-195) μg/L in exclusively breastfeeding, 57 (28-123) μg/L in formula feeding, and 45 (35-132) μg/L in mixed feeding, with no statistically significant difference between the groups (P = .31). The median (IQR) breast milk iodine concentration was 271 (177-521) μg/L in preterm infants exclusively fed their mothers’ own milk. There was no significant difference in the proportion of the TSH levels of >5 mIU/L between preterm infants who received enteral and parenteral nutrition (P = .27). Conclusion: Preterm infants are at risk of iodine deficiency even in an area where the general population has adequate iodine. Only the preterm infants who received exclusively their mothers’ own milk had marginally adequate iodine status. Further studies are warranted to determine the necessity of iodine supplementation for this vulnerable group. © 2022 AACE

Related Docs

View other Related Docs

1. Lactating Mothers and Infants Residing in an Area With an Effective Salt Iodization Program Have No Need for Iodine Supplements: Results From a Double-Blind, Placebo-Controlled, Randomized Controlled Trial, Thyroid (2018)

2. Maternal Urinary Iodine Concentration and Pregnancy Outcomes: Tehran Thyroid and Pregnancy Study, Biological Trace Element Research (2020)

3. Is There Any Difference Between the Iodine Statuses of Breast-Fed and Formula-Fed Infants and Their Mothers in an Area With Iodine Sufficiency?, British Journal of Nutrition (2018)

4. Application of Povdone-Iodine at Delivery Significantly Increases Maternal Urinary Iodine But Not Neonatal Thyrotropin in an Area With Iodine Sufficiency, Journal of Pediatric Endocrinology and Metabolism (2017)

5. Urinary and Breast Milk Iodine Concentrations in Lactating Mothers and Its Association With Certain Demographic Characteristics in an Area With Iodine Sufficiency, Iranian Journal of Endocrinology and Metabolism (2018)

6. The Impact of Iodine Status on the Recall Rate of the Screening Program for Congenital Hypothyroidism: Findings From Two National Studies in Iran, Nutrients (2017)

7. Do Postpartum Maternal Iodine Status or Supplementation Affect Thyroid Function After Delivery? a Systematic Review and Meta-Analysis, Biological Trace Element Research (2023)

8. Breast Milk Iodine Concentration Rather Than Maternal Urinary Iodine Is a Reliable Indicator for Monitoring Iodine Status of Breastfed Neonates, Biological Trace Element Research (2018)

Experts (# of related papers)

View all Related Experts

Pantea Nazeri Kahgani (9)

Hossein Dalili (2)

Style	Citing Format
MLA	Nazeri P, et al.. "Iodine Status of Preterm Infants Born in an Area of Iodine Sufficiency: Are They at Risk of Iodine Deficiency?." Endocrine Practice, vol. 28, no. 9, 2022, pp. 835-841.
APA	Nazeri P, Akbarzadeh M, Pearce EN, Hedayati M, Dalili H (2022). Iodine Status of Preterm Infants Born in an Area of Iodine Sufficiency: Are They at Risk of Iodine Deficiency?. Endocrine Practice, 28(9), 835-841.
Chicago	Nazeri P, Akbarzadeh M, Pearce EN, Hedayati M, Dalili H. "Iodine Status of Preterm Infants Born in an Area of Iodine Sufficiency: Are They at Risk of Iodine Deficiency?." Endocrine Practice 28, no. 9 (2022): 835-841.
Harvard	Nazeri P et al. (2022) 'Iodine Status of Preterm Infants Born in an Area of Iodine Sufficiency: Are They at Risk of Iodine Deficiency?', Endocrine Practice, 28(9), pp. 835-841.
Vancouver	Nazeri P, Akbarzadeh M, Pearce EN, Hedayati M, Dalili H. Iodine Status of Preterm Infants Born in an Area of Iodine Sufficiency: Are They at Risk of Iodine Deficiency?. Endocrine Practice. 2022;28(9):835-841.
BibTex	@article{ author = {Nazeri P and Akbarzadeh M and Pearce EN and Hedayati M and Dalili H}, title = {Iodine Status of Preterm Infants Born in an Area of Iodine Sufficiency: Are They at Risk of Iodine Deficiency?}, journal = {Endocrine Practice}, volume = {28}, number = {9}, pages = {835-841}, year = {2022} }
RIS	TY - JOUR AU - Nazeri P AU - Akbarzadeh M AU - Pearce EN AU - Hedayati M AU - Dalili H TI - Iodine Status of Preterm Infants Born in an Area of Iodine Sufficiency: Are They at Risk of Iodine Deficiency? JO - Endocrine Practice VL - 28 IS - 9 SP - 835 EP - 841 PY - 2022 ER -

Science Communicator Platform

Authors

Authors Affiliations

Abstract