Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Low Bone Mineral Density and Associated Factors Among People Living With Hiv in Kerman, Iran: A Cross-Sectional Study in 2021-2022 Publisher Pubmed



Rashidi H1, 2, 10 ; Mehmandoost S1, 2, 10 ; Fahimfar N3 ; Aghaei Meybodi HR4 ; Hosseinian SM5, 9 ; Shirzad N6 ; Hajivalizade F7 ; Sanjari M8, 11, 13 ; Shakibi MR5, 9 ; Hasan Aghaei T5, 9 ; Yazdi Yahaabadi F5, 9 ; Salajegheh P12 ; Shafiee G8, 11, 13 ; Razi F14 Show All Authors
Authors
  1. Rashidi H1, 2, 10
  2. Mehmandoost S1, 2, 10
  3. Fahimfar N3
  4. Aghaei Meybodi HR4
  5. Hosseinian SM5, 9
  6. Shirzad N6
  7. Hajivalizade F7
  8. Sanjari M8, 11, 13
  9. Shakibi MR5, 9
  10. Hasan Aghaei T5, 9
  11. Yazdi Yahaabadi F5, 9
  12. Salajegheh P12
  13. Shafiee G8, 11, 13
  14. Razi F14
  15. Ranjbar E15
  16. Mcfarland W16
  17. Ostovar A8, 11, 13
  18. Sharifi H1, 2, 10
Show Affiliations
Authors Affiliations
  1. 1. HIV/STI Surveillance Research Center, WHO Collaborating Center for HIV Surveillance, Kerman University of Medical Sciences, Kerman, Iran
  2. 2. HIV/STI Surveillance Research Center, WHO Collaborating Center for HIV Surveillance, Kerman University of Medical Sciences, Kerman, Iran
  3. 3. Osteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, The Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Evidence-Based Medicine Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Rheumatology Department, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran
  6. 6. Endocrine Research Center, Valiasr Hospital, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
  7. 7. Noncommunicable Disease Center, Ministry of Health, Tehran, Iran
  8. 8. Osteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  9. 9. Rheumatology Department, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran
  10. 10. HIV/STI Surveillance Research Center, WHO Collaborating Center for HIV Surveillance, Kerman University of Medical Sciences, Kerman, Iran
  11. 11. Osteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  12. 12. The Pediatric Department, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran
  13. 13. Osteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  14. 14. The Metabolomics and Genomics Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  15. 15. HIV Voluntary Counselling and Testing Center, Kerman University of Medical Sciences, Kerman, Iran
  16. 16. UCSF School of Medicine, United States

Source: Journal of the Association of Nurses in AIDS Care Published:2025


Abstract

Chronic diseases such as osteoporosis and low bone mineral density (BMD) are significant public health concerns for people living with HIV (PLWH), especially with the increased life expectancy because of antiretroviral therapy (ART). This study evaluated the prevalence and associated factors of low BMD among 94 PLWH in Kerman, Iran, from September 2021 to February 2022. Using dual-energy X-ray absorptiometry, BMD was measured, with low BMD defined by specific T-scores and Z-scores. Predictors were assessed through interviews, medical records, and blood tests. Bivariable and multivariable logistic regression models identified associations between low BMD and various factors. The study found a 51.1% prevalence of low BMD, with significant associations with hypogonadism (adjusted odds ratio [aOR]: 3.19), longer ART duration (aOR per month: 1.02), and lower body mass index (aOR per unit: 0.83). The findings highlight the need for regular screening and timely intervention for low BMD among PLWH, particularly with prolonged ART use. Copyright © 2025 Association of Nurses in AIDS Care.
Related Docs
View other Related Docs
1. Cumulative Incidence and Treatment Effectiveness of Low Bone Mineral Density Among People Living With Hiv in Iran (2021–2023), AIDS Research and Therapy (2024)
2. Evaluation of Bone Mineral Density and Its Influencing Factors in Patients Infected With Hiv Under Antiretroviral Therapy, BMC Infectious Diseases (2025)
3. Effects of Metabolic Dysfunction-Associated Steatotic Liver Disease on Bone Density and Fragility Fractures: Associations and Mechanisms, Journal of Obesity and Metabolic Syndrome (2024)
4. The Association Between Anti-Diabetic Agents and Osteoporosis, Sarcopenia, and Osteosarcopenia Among Iranian Older Adults; Bushehr Elderly Health (Beh) Program, DARU# Journal of Pharmaceutical Sciences (2024)
5. The Association Between Osteoporosis and Quality of Life Among Older Adults in Southern Iran: Findings From the Bushehr Elderly Health Program, BMC Geriatrics (2024)
6. The Reference Value of Trabecular Bone Score (Tbs) in the Iranian Population, Journal of Diabetes and Metabolic Disorders (2020)
7. Prevalent Osteoporosis and Fracture Risk in Patients With Hepatic Cirrhosis: A Systematic Review and Meta-Analysis, BMC Gastroenterology (2025)
8. Osteoporosis E-Learning Courses: A Systematic Review to Develop a Comprehensive Virtual Course for General Practitioners, Journal of Diabetes and Metabolic Disorders (2023)
Experts (# of related papers)
View all Related Experts
Noushin Fahimfar (7)
Afshin Ostovar (7)
Other Related Docs
9. Prevalence of Osteoporosis Among the Elderly Population of Iran, Archives of Osteoporosis (2021)
10. Neural Egfl Like 1 As a Novel Gene for Trabecular Bone Score in Older Adults: The Bushehr Elderly Health (Beh) Program, PLoS ONE (2024)