Evaluation of the Efficacy of Topical Sucralfate on Healing Haemorrhoidectomy Incision Wounds and Reducing Pain Severity: A Randomised Clinical Trial Publisher Pubmed



Vejdan AK¹ ; Khosravi M² ; Amirian Z³ ; Daneshmand M⁴ ; Babak B⁴ ; Samira K⁴ ; Azin S⁴ ; Kosar S⁴ ; Razie K⁴
Source: International Wound Journal Published:2020

Abstract

The healing of haemorrhoidectomy wounds is a main concern of surgeons and patients. Various modalities can improve the quality of wound care after surgery. Antibiotics and topical agents, such as solutions and ointments, have been evaluated. The current research investigates the effects of sucralfate ointment on wound healing (epithelialisation) and postoperative pain after open haemorrhoidectomy. This trial involves two groups of randomly collected patients (n = 40) who underwent open haemorrhoidectomy surgery by the Milligan-Morgan method. A 10% topical sucralfate ointment was applied to the investigated group's wounds, while the control group patients used Vaseline as a placebo. The present work measured the two outcomes as follows: pain severity by a Visual Analogues Scale (VAS) score and epithelialisation by a surgeon's visual inspection. During the postoperative phase, the mean VAS was 3.70 for the investigated group and 6.90 for the control group. On the average, the completion of epithelialisation for the investigated group was on day 13 as opposed to day 20 for the control group. The topical application of sucralfate ointment on post-haemorrhoidectomy wound is an effective method for the promotion of healing, also lessens the severity of pain, and reduces the need for analgesics. © 2020 Medicalhelplines.com Inc and John Wiley & Sons Ltd