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Effect of Achillea Vermicularis Ointment on Wound Healing After Episiotomy in Primiparous Women: A Randomised Clinical Trial Publisher



Rahmani A1 ; Fedotova J2 ; Rezaei E4 ; Shahbazi Sighaldeh S5 ; Fallahi A6 ; Allahqoli L7 ; Ghanei Gheshlagh R8 ; Sadati Lamardi SN9 ; Alkatout I10
Authors
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Authors Affiliations
  1. 1. Nursing and Midwifery Care Research Center, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Laboratory of Neuroendocrinology, I.P. Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg, Russia
  3. 3. School of Medical Biology, South Ural State University, Chelyabinsk, Russian Federation
  4. 4. Midwifery department, School of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran
  5. 5. Midwifery and reproductive health department, Nursing and Midwifery School, Tehran Uiversity of Medical Sciences, Tehran, Iran
  6. 6. Associate Professor, Department of Public Health, Faculty of Health, Kurdistan University of Medical Sciences, Sanandaj, Iran
  7. 7. Midwifery Department, Ministry of Health and Medical Education, Tehran, Iran
  8. 8. Social Determinants of Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran
  9. 9. Department of Traditional Pharmacy, School of Traditional Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran
  10. 10. University Hospital Schleswig-Holstein, Campus Kiel, Kiel School of Gynaecological Endoscopy, Arnold-Heller-Str. 3, Haus 24, Kiel, 24105, Germany

Source: Journal of Herbal Medicine Published:2023


Abstract

Introduction: Episiotomy may be followed by several maternal complications, such as postpartum infection, pain, discomfort, and prolonged wound healing. The present study was conducted to evaluate the effect of Achillea vermicularis on wound healing after episiotomy. Methods: We performed a randomised clinical trial consisting of 100 participants aged on average 23.37 (±4.96) years, who underwent an episiotomy during normal vaginal delivery from June to December 2018. The mothers were randomly allocated to the treatment or control group. Those in the treatment group used the A. vermicularis 3% ointment, while those in the control group received routine treatment consisting of sitz baths with betadine solution. The primary outcome was wound healing, which was assessed using the redness, edema, ecchymosis, discharge, and approximation (REEDA) scale on baseline and days 7 and 10 after the intervention. Results: The episiotomy wound parameters did not differ significantly between groups on day 7, but there was a significant difference in redness (P = 0.02), discharge (P = 0.03), approximation of wound edges (P = 0.03), and wound healing (P < 0.001) between the two groups on day 10. Discussion: It may be concluded that A. vermicularis ointment has a positive effect on wound healing after episiotomy on day 10 postpartum. © 2023 Elsevier GmbH
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