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Immediate and Long-Term Effects of a Computerized Cognitive Rehabilitation Therapy on Cognitive Function in People Living With Hiv in Iran: A Single-Blind Two-Arm Parallel Randomized Controlled Trial Publisher Pubmed



Etesami MS1, 2, 3 ; Saboury N4 ; Mohraz M5 ; Seyedalinaghi S6 ; Jones DL7 ; Vance DE8 ; Habibi Asgarabad M3, 9, 10, 11
Authors
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Authors Affiliations
  1. 1. Clinical Psychologist and Researcher, Iranian Research Center for HIV/AIDS (IRCHA), Imam Khomeini Hospital Complex, Iran
  2. 2. Health Promotion Research Center, Iran University of Medical Sciences, Iran
  3. 3. Center of Excellence in Cognitive Neuropsychology, Institute for Cognitive and Brain Sciences, Shahid Beheshti University, Tehran, Iran
  4. 4. Department of Psychology, Faculty of Humanities, University of Science and Culture, Tehran, Iran
  5. 5. Iranian Research Center for HIV/AIDS (IRCHA), Department of Infectious Diseases, Imam Khomeini Hospital Complex, Tehran, Iran
  6. 6. Iranian Research Center for HIV/AIDS (IRCHA), Iranian Institute for Reduction of High-Risk Behaviors, Tehran University of Medical Sciences, Tehran, Iran
  7. 7. Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL, United States
  8. 8. School of Nursing, University of Alabama at Birmingham, Birmingham, AL, United States
  9. 9. Health Promotion Research Center, Iran University of Medical Sciences, Tehran, Iran
  10. 10. Department of Health Psychology, School of Behavioral Sciences and Mental Health, Tehran Institute of Psychiatry, Iran University of Medical Sciences, Iran
  11. 11. Department of Psychology, Norwegian University of Science and Technology, Trondheim, Norway

Source: Journal of the Association of Nurses in AIDS Care Published:2022


Abstract

Up to 50% of people with HIV (PWH) experience neurocognitive impairments (NCIs) that can interfere with everyday functioning and reduce quality of life. To address this problem, this study examined the immediate and long-term efficacy of computerized cognitive rehabilitation therapy (CCRT) on cognitive function in PWH in Tehran, Iran. Thirty PWH with NCI engaged in 24 biweekly 90-min CCRT sessions. A control group of 30 PWH and NCI received treatment-as-usual, but no CCRT. The cognitive rehabilitation protocol focused on attention, visual memory, nonverbal learning, and planning. Pretest, posttest, and follow-up cognitive measurements showed that the designed CCRT protocol was effective in improving performance in selected cognitive domains along with the global neurocognitive performance scores of PWH. These findings suggest that this CCRT protocol be considered as part of a treatment plan to address cognitive impairment for PWH. Implications for clinical practice and research are provided. © 2022 Elsevier USA. All rights reserved.
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