Nanotechnology in Dental Implants: Impact of Nanoceramics on Osseointegration—A Systematic Review Publisher



Saini RS ; Binduhayyim RIH ; Madhav VNV ; Gurumurthy V ; Lomelimartinez SM ; Alarconsanchez MA ; Floresfraile J ; Heboyan A
Source: Journal of Chemical Research Published:2026

Abstract

The field of dental implants underwent a transformation with nanotechnology, which promises enhanced bone alignment and increased antibacterial properties. The systematic review evaluated the latest evidence about nanoceramic coatings in dental implants and their effects on clinical outcomes. The research team conducted a systematic literature search across multiple databases, including PubMed, ScienceDirect, Scopus, Google Scholar, and The Cochrane Library to locate studies published between January 2004 and June 2024 and performed this search following PRISMA guidelines. Selected studies evaluated dental implants enhanced with nanoceramic coatings or modifications concerning osseointegration rates, antimicrobial efficacy, biocompatibility, and implant stability. Two researchers individually evaluated data selection and quality using the QUIN quality assessment tool. This review included 10 studies, and different nanoceramic coating techniques, such as immersion coating, spin coating, and fabrication, were identified. The results showed that nanoceramic coating significantly improved osseointegration. Antimicrobial properties were remarkably enhanced, with nanoparticle-treated surfaces effectively inhibiting bacterial growth. Biocompatibility assessments demonstrated that nanoceramic-coated implants supported cell viability and proliferation, while stability tests indicated improved implant integration and mechanical strength. All studies were of medium methodological quality. Nanotechnology shows great promise for improving the function of dental implants. Advanced osseointegration, with high antibacterial properties and biocompatibility, suggests that nanoceramic-coating implants have better clinical outcomes. Future research should focus on long-term clinical trials to establish these findings and highlight and explore the potential of various nanoceramic materials in clinical settings. © The Author(s) 2026. This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).