Central Odontogenic Fibroma Accompanied by a Central Giant Cell Granuloma-Like Lesion: Report of a Case and Review of Literature

Central Odontogenic Fibroma Accompanied by a Central Giant Cell Granuloma-Like Lesion: Report of a Case and Review of Literature Publisher

Moradzadeh Khiavi M¹ ; Karimi A² ; Sadeghi HM³ ; Derakhshan S¹ ; Tafreshi SM⁴ ; Jalali S⁴

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1. Department of Oral and Maxillofacial Pathology, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran
2. Department of Oral and Maxillofacial Surgery, School of Dentistry, Craniomaxillofacial Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
3. Department of Oral & Maxillofacial Surgery, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran
4. Private Practice, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran

Source: Frontiers in Dentistry Published:2021

Abstract

Central giant cell granuloma (CGCG) is a benign non-neoplastic intraosseous lesion mainly found in the anterior mandible. It is characterized by multinucleated giant cells, representing osteoclasts or macrophages. Central odontogenic fibroma (COF) is an uncommon benign lesion of the jaws. It originates from the odontogenic ectomesenchyme. In rare cases, COF may accompany a CGCG. To date, 49 cases of COF accompanied by CGCG-like lesions have been reported in the literature. In this paper, we present another case of COF-CGCG in a 46-year-old female. The lesion was located in the posterior mandible. Excisional biopsy was carried out, and histopathological analysis revealed multinucleated giant cells with numerous strands of odontogenic epithelium. A literature review of previously reported cases was also performed. © The Authors.

Style	Citing Format
MLA	Moradzadeh Khiavi M, et al.. "Central Odontogenic Fibroma Accompanied by a Central Giant Cell Granuloma-Like Lesion: Report of a Case and Review of Literature." Frontiers in Dentistry, vol. 18, no. , 2021, pp. -.
APA	Moradzadeh Khiavi M, Karimi A, Sadeghi HM, Derakhshan S, Tafreshi SM, Jalali S (2021). Central Odontogenic Fibroma Accompanied by a Central Giant Cell Granuloma-Like Lesion: Report of a Case and Review of Literature. Frontiers in Dentistry, 18(), -.
Chicago	Moradzadeh Khiavi M, Karimi A, Sadeghi HM, Derakhshan S, Tafreshi SM, Jalali S. "Central Odontogenic Fibroma Accompanied by a Central Giant Cell Granuloma-Like Lesion: Report of a Case and Review of Literature." Frontiers in Dentistry 18, no. (2021): -.
Harvard	Moradzadeh Khiavi M et al. (2021) 'Central Odontogenic Fibroma Accompanied by a Central Giant Cell Granuloma-Like Lesion: Report of a Case and Review of Literature', Frontiers in Dentistry, 18(), pp. -.
Vancouver	Moradzadeh Khiavi M, Karimi A, Sadeghi HM, Derakhshan S, Tafreshi SM, Jalali S. Central Odontogenic Fibroma Accompanied by a Central Giant Cell Granuloma-Like Lesion: Report of a Case and Review of Literature. Frontiers in Dentistry. 2021;18():-.
BibTex	@article{ author = {Moradzadeh Khiavi M and Karimi A and Sadeghi HM and Derakhshan S and Tafreshi SM and Jalali S}, title = {Central Odontogenic Fibroma Accompanied by a Central Giant Cell Granuloma-Like Lesion: Report of a Case and Review of Literature}, journal = {Frontiers in Dentistry}, volume = {18}, number = {}, pages = {-}, year = {2021} }
RIS	TY - JOUR AU - Moradzadeh Khiavi M AU - Karimi A AU - Sadeghi HM AU - Derakhshan S AU - Tafreshi SM AU - Jalali S TI - Central Odontogenic Fibroma Accompanied by a Central Giant Cell Granuloma-Like Lesion: Report of a Case and Review of Literature JO - Frontiers in Dentistry VL - 18 IS - SP - EP - PY - 2021 ER -

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