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Dinitrophenols Publisher



Nasab MHF1, 2 ; Manavi MA1, 2 ; Baeeri M1, 2, 3
Authors
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Authors Affiliations
  1. 1. Department of Toxicology and Pharmacology, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Toxicology and Pharmacology, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Toxicology and Diseases Group, Pharmaceutical Sciences Research Center (PSRC), The Institute of Pharmaceutical Sciences (TIPS), Tehran University of Medical Sciences, Tehran, Iran

Source: Encyclopedia of Toxicology# Fourth Edition: Volume 1-9 Published:2023


Abstract

In France, during World War I, 2,4-dinitrophenol (DNP), a crystalline solid with a yellow tint, was utilized to make munitions. At the same time, the FDA forbade the ingestion of DNP in 1983. In addition to insecticides, DNP is used to create colors, wood preservatives, pH indicators, and explosive materials. DNP is quickly absorbed in the digestive system. Long-term DNP exposure causes skeletal, liver, renal, cutaneous, lymphoreticular, and immunologic effects in humans. © 2024 Elsevier Inc. All rights reserved.