Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
At Least Eighty Percent of Brain Grey Matter Is Modifiable by Physical Activity: A Review Study Publisher Pubmed



Batouli SAH1, 2 ; Saba V3
Authors
Show Affiliations
Authors Affiliations
  1. 1. Neuroimaging and Analysis Group, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Faculty of Paramedicine, Aja University of Medical Sciences, Tehran, Iran

Source: Behavioural Brain Research Published:2017


Abstract

The human brain is plastic, i.e. it can show structural changes in response to the altered environment. Physical activity (PA) is a lifestyle factor which has significant associations with the structural and functional aspects of the human brain, as well as with the mind and body health. Many studies have reported regional/global brain volume increments due to exercising; however, a map which shows the overall extent of the influences of PAs on brain structure is not available. In this study, we collected all the reports on brain structural alterations in association with PA in healthy humans, and next, a brain map of the extent of these effects is provided. The results of this study showed that a large network of brain areas, equal to 82% of the total grey matter volume, were associated with PA. This finding has important implications in utilizing PA as a mediator factor for educational purposes in children, rehabilitation applications in patients, improving the cognitive abilities of the human brain such as in learning or memory, and preventing age-related brain deteriorations. © 2017 Elsevier B.V.
Related Docs
View other Related Docs
1. Iranian Brain Imaging Database: A Neuropsychiatric Database of Healthy Brain, Basic and Clinical Neuroscience (2021)
2. Cognitive Dysfunction and Exercise: From Epigenetic to Genetic Molecular Mechanisms, Molecular Neurobiology (2024)
3. Exercise Training Improves Memory Performance in Older Adults: A Narrative Review of Evidence and Possible Mechanisms, Frontiers in Human Neuroscience (2022)
4. The Volumetric Changes of the Pineal Gland With Age: An Atlas-Based Structural Analysis, Experimental Aging Research (2022)
5. Some Points to Consider in a Task-Based Fmri Study: A Guideline for Beginners, Frontiers in Biomedical Technologies (2020)
6. Physical Activity May Contribute to Brain Health in Multiple Sclerosis: An Mr Volumetric and Spectroscopy Study, Journal of Neuroimaging (2021)
7. Adult Hippocampal Neurogenesis (Ahn) Controls Central Nervous System and Promotes Peripheral Nervous System Regeneration Via Physical Exercise, Biomedicine and Pharmacotherapy (2023)
8. A Probabilistic Atlas of the Pineal Gland in the Standard Space, Frontiers in Neuroinformatics (2021)
Experts (# of related papers)
View all Related Experts
Seyed Amir Hossein Batouli (5)
Mohammad Sharifzadeh (2)
Other Related Docs
9. Along-Tract Analysis of the White Matter Is More Informative About Brain Ageing, Compared to Whole-Tract Analysis, Clinical Neurology and Neurosurgery (2021)
10. Dual-Task Training Affect Cognitive and Physical Performances and Brain Oscillation Ratio of Patients With Alzheimer’S Disease: A Randomized Controlled Trial, Frontiers in Aging Neuroscience (2020)
11. Complicated Role of Exercise in Modulating Memory: A Discussion of the Mechanisms Involved, Neurochemical Research (2022)
12. Handgrip Strength and Gait Speed Relationships With Cognitive Impairment in Iranian Older Adults: Birjand Longitudinal Aging Study, Geriatric Nursing (2025)
13. The Effects of Different Protocols of Physical Exercise and Rest on Long-Term Memory, Neurobiology of Learning and Memory (2020)
14. Maternal Voluntary Exercise Ameliorates Learning Deficit in Rat Pups Exposed, in Utero, to Valproic Acid; Role of Bdnf and Vegf and Their Receptors, Neuropeptides (2018)
15. The Effect of Exercise Therapy on Cognitive Functions in Multiple Sclerosis Patients: A Pilot Study, Medical Journal of the Islamic Republic of Iran (2015)
16. Protective Effects of Physical Exercise on Mdma-Induced Cognitive and Mitochondrial Impairment, Free Radical Biology and Medicine (2016)
17. Mitochondrial Impairments Contribute to Spatial Learning and Memory Dysfunction Induced by Chronic Tramadol Administration in Rat: Protective Effect of Physical Exercise, Progress in Neuro-Psychopharmacology and Biological Psychiatry (2017)