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Familial Hypokalemic Periodic Paralysis Attack Following Sars- Cov- 2 Infection: A Case Report Publisher



Yousefimazhin E1 ; Karballaeimirzahosseini H1 ; Sharifnia H2 ; Najafi A2 ; Najmeddin F1 ; Tofighimohammadi M1 ; Hassanpour R1 ; Mojtahedzadeh M1
Authors
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Authors Affiliations
  1. 1. Department of Clinical Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Anesthesiology, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran

Source: Archives of Anesthesiology and Critical Care Published:2024


Abstract

Familial hypokalemic periodic paralysis is a rare disorder that manifests manifests with the sudden onset of flaccid paralysis that is triggered by low levels of blood potassium, which can be caused by various factors such as, rest after intense exercise, or high-carbohydrate foods. This report presents cases of hypokalemic periodic paralysis attack triggered by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. A 29-year-old male patient was admitted with quadriparesis, fever, shortness of breath, and sever hypokalemia. The patient had a history of three episodes of Familial hypokalemic periodic paralysis (HPP). Diagnostic tests, such as chest computed tomography scan and polymerase chain reaction test, confirmed SARS-CoV-2 infection. The patient was treated with potassium chloride infusion, spironolactone, and remdesivir, and was eventually discharged from the hospital.in conclusion, SARS-CoV-2 infection can potentially exacerbate HPP and should be considered a risk factor for its occurrence. © 2024 Tehran University of Medical Sciences.