The Association Between Resting Metabolic Rate and Metabolic Syndrome May Be Mediated by Adipokines in Overweight and Obese Women

The Association Between Resting Metabolic Rate and Metabolic Syndrome May Be Mediated by Adipokines in Overweight and Obese Women Publisher Pubmed

Sepandar F^{1, 2} ; Rashidbeygi E² ; Maghbooli Z³ ; Khorraminezhad L² ; Hajizadehoghaz M⁴ ; Mirzaei K²

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1. Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences (TUMS), Tehran, Iran
2. Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences (TUMS), P.O. Box: 14155-6117, Tehran, Iran
3. Multiple Sclerosis Research Center, Sina Hospital, Tehran University of Medical Sciences, Iran
4. University of Nebraska-Lincoln, United States

Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews Published:2019

Abstract

Aims: Adipokines play a major role in developing metabolic syndrome (MetS), and it has been found that there is a significant relationship between MetS and resting metabolic rate (RMR) in obese people. The present study aimed to investigate the mediatory effect of adipokines on the RMR-MetS relationship. Methods: This cross-sectional study included 263 obese and overweight women, mean BMI 33.28 (4.93) kg/m, and mean age 39.02 (11.60) who were assessed for RMR using indirect calorimetry. Moreover, using the body composition analyzer the Body composition was measured. Also, Enzyme-linked Immunosorbent Assay (ELISA) test provided a quantitative measurement of biochemical parameters. Results: The results indicated that women in low RMR group had higher fat mass (P < 0.0001), FFM (P = 0.002), weight (P = 0.006), BMI (P < 0.0001), age (P = 0.01), and hs-CRP (P = 0.001). The results did not confirm any significant mediating roles for RBP4 (P = 0.051, β = −0.28) and Vaspin (P = 0.06, β = 0.32) in the RMR-MetS relationship. Additionally, after a binary regression test, Omentin-1 showed a significant mediating role (P = 0.25, β = 0.04) as an interrelated agent to RMR and MetS. Conclusion: As this study shows, Omentin-1 was found to play a significant mediating role as a mediatory agent in relationship between RMR and MetS. © 2018

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Khadijeh Mirzaei (12)

Zhila Maghbooli Taghi Dizaj (3)

Style	Citing Format
MLA	Sepandar F, et al.. "The Association Between Resting Metabolic Rate and Metabolic Syndrome May Be Mediated by Adipokines in Overweight and Obese Women." Diabetes and Metabolic Syndrome: Clinical Research and Reviews, vol. 13, no. 1, 2019, pp. 530-534.
APA	Sepandar F, Rashidbeygi E, Maghbooli Z, Khorraminezhad L, Hajizadehoghaz M, Mirzaei K (2019). The Association Between Resting Metabolic Rate and Metabolic Syndrome May Be Mediated by Adipokines in Overweight and Obese Women. Diabetes and Metabolic Syndrome: Clinical Research and Reviews, 13(1), 530-534.
Chicago	Sepandar F, Rashidbeygi E, Maghbooli Z, Khorraminezhad L, Hajizadehoghaz M, Mirzaei K. "The Association Between Resting Metabolic Rate and Metabolic Syndrome May Be Mediated by Adipokines in Overweight and Obese Women." Diabetes and Metabolic Syndrome: Clinical Research and Reviews 13, no. 1 (2019): 530-534.
Harvard	Sepandar F et al. (2019) 'The Association Between Resting Metabolic Rate and Metabolic Syndrome May Be Mediated by Adipokines in Overweight and Obese Women', Diabetes and Metabolic Syndrome: Clinical Research and Reviews, 13(1), pp. 530-534.
Vancouver	Sepandar F, Rashidbeygi E, Maghbooli Z, Khorraminezhad L, Hajizadehoghaz M, Mirzaei K. The Association Between Resting Metabolic Rate and Metabolic Syndrome May Be Mediated by Adipokines in Overweight and Obese Women. Diabetes and Metabolic Syndrome: Clinical Research and Reviews. 2019;13(1):530-534.
BibTex	@article{ author = {Sepandar F and Rashidbeygi E and Maghbooli Z and Khorraminezhad L and Hajizadehoghaz M and Mirzaei K}, title = {The Association Between Resting Metabolic Rate and Metabolic Syndrome May Be Mediated by Adipokines in Overweight and Obese Women}, journal = {Diabetes and Metabolic Syndrome: Clinical Research and Reviews}, volume = {13}, number = {1}, pages = {530-534}, year = {2019} }
RIS	TY - JOUR AU - Sepandar F AU - Rashidbeygi E AU - Maghbooli Z AU - Khorraminezhad L AU - Hajizadehoghaz M AU - Mirzaei K TI - The Association Between Resting Metabolic Rate and Metabolic Syndrome May Be Mediated by Adipokines in Overweight and Obese Women JO - Diabetes and Metabolic Syndrome: Clinical Research and Reviews VL - 13 IS - 1 SP - 530 EP - 534 PY - 2019 ER -

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