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Biosensor-Based Methods for Crimean-Congo Hemorrhagic Fever Virus Detection Publisher Pubmed



Zandi M1 ; Rasooli A2, 3 ; Soltani S1 ; Teymouri S4 ; Mohammadi S5 ; Abbasi S6
Authors
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Authors Affiliations
  1. 1. Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Biochemistry, Faculty of Sciences, Payame Noor University, Tehran, Iran
  3. 3. Virology Department, Pasteur Institute of Tehran, Tehran, Iran
  4. 4. Microbial Biotechnology Research Center, Department of Microbiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
  5. 5. Neuroscience and Addiction Studies Department, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Department of Microbiology, School of Medicine, Abadan University of Medical Sciences, Abadan, Iran

Source: Journal of Vector Borne Diseases Published:2021


Abstract

Crimean-Congo hemorrhagic fever is a tick-borne disease with high fatality rate that is endemic in some parts of Asia, Africa and Europe. Rapid diagnostics of Crimean-Congo hemorrhagic fever (CCHF) is necessary for appropriate clinical management of this disease and also can be useful in preventing of secondary spread from human-to-human, though, common tests which are used to diagnose Crimean-Congo hemorrhagic fever have some limitations. Here we review 1) common diagnostic tests for CCHF, 2) limitations in laboratories methods of CCHF and 3) biosensor researches for detection of CCHF. It is necessary to design and develop an effective, rapid, and also low-cost tool such as biosensor to detect Crimean-Congo hemorrhagic fever. Based on the key role of rapid detection of CCHF in the control of infection, development of a biosensor as a rapid tool seems very major in the diagnosis of CCHF, though, there are limited studies on this field and more researches are needed in this issue. © 2021 Wolters Kluwer Medknow Publications. All rights reserved.
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