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Crimean-Congo Hemorrhagic Fever Virus Vaccine: Past, Present, and Future Publisher



Behboudi E1 ; Kakavandi E2, 3 ; Hamidisofiani V1 ; Ebrahimian A1 ; Shayestehpour M4, 5
Authors
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Authors Affiliations
  1. 1. Department of Microbiology, Golestan University of Medical Sciences, Gorgan, Iran
  2. 2. Department of Virology, School of Public Health, Iran
  3. 3. Students' Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Autoimmune Diseases Research Center, Iran
  5. 5. Department of Microbiology and Immunology, Faculty of Medicine, Kashan University of Medical Sciences, PO Box 8715988141, e Ravandi Blvd, Kashan, Iran

Source: Reviews and Research in Medical Microbiology Published:2022


Abstract

Crimean-Congo hemorrhagic fever (CCHF) has been recognized as a tick-borne infection caused by a member of the Nairoviridae family within the Bunyavirales order, named CCHF virus. CCHF virus is a zoonotic virus, so transferred between vertebrates and humans. Therefore, vaccination in humans and animals might reduce the risk of infection. Currently, there are no globally licensed vaccines or therapeutics for CCHF. Although several studies have been performed on the production of the CCHF vaccine, any of these vaccines were not fully protective. Hence, the development of a new generation of vaccines could contribute to better management of CCHF. In this review, we will discuss on features of these vaccine candidates. © 2022 Lippincott Williams and Wilkins. All rights reserved.
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