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Severity of Mitral Regurgitation Before and After Kidney Transplantation



Pourmand G1 ; Saleh SK2 ; Mehrsai A1 ; Gooran S1 ; Khajavi M1 ; Razeghi E1 ; Rahbar M1 ; Pourhossein M1 ; Dehghani S1
Authors
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Authors Affiliations
  1. 1. Urology Research Center, Tehran University of Medical Science, Tehran, Iran
  2. 2. Department of Cardiology, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran

Source: International Journal of Organ Transplantation Medicine Published:2019

Abstract

Background: Perivalvular and valve involvement are prevalent in patients with end-stage renal disease (ESRD), especially in younger patients compared with normal population. Kidney transplantation improves the prognosis of these patients. Patients with cardiac valvular disease is also be improved following kidney transplantation. Objective: To evaluate the impact of renal transplantation on the severity of mitral regurgitation (MR). Methods: We studied 95 kidney transplantation candidates in Sina Hospital. The patients underwent echocardiography preoperatively and at the 3rd, 6th, and 12th months post-operatively. Results: Pre-operatively, the average MR fraction was 30%; MR volume 30 mL/beat; mitral valve mean gradient 1.8 mm Hg; mitral valve area 4.6 cm2; and mitral annular size 3 cm. No significant difference was observed among the measurements made at the 3rd, 6th, and 12th months post-operatively. Conclusion: There was no significant association between the variables measured pre- and post-operatively. The reason might be the fact that patients with ESRD in Iran do not have to expect long transplant waiting lists and dialysis cannot affect their heart adversely. © 2019 Iranian Society for Organ Transplantation.