Addressing the Challenge of Obesity in Primary Care: A Review of Effective Interventions and Implementation Strategies Publisher



M Khani MAHAN ; R Afsahi REZA ; Ae Nasab Ali EBRAHIMI ; Sh Biaragh Sina HEMMATI ; K Rasouli KIMIA ; Mh Ahangar Mehdi HASSANI ; As Soltani Abbas SARVARI ; R Pourahmad RAMTIN
Source: Diabetology and Metabolic Syndrome Published:2025

Abstract

Obesity is a worldwide health epidemic that significantly raises morbidity and mortality by means of related comorbidities including diabetes and cardiovascular diseases. By means of effective interventions including behavioral therapies, comprehensive lifestyle modifications, and an increasing armamentarium of pharmacological agents capable of appreciable weight loss, primary care physicians are especially positioned to contribute significantly to the management of obesity. This review summarizes the most recent studies on behavioral interventions (such as cognitive behavioral therapy and motivational interviewing), pharmacological treatment options (including recently approved and emerging agents), and lifestyle changes (such diet and physical activity) in order to manage obesity in primary care environments. It also addresses the several challenges this field faces—including weight stigma and systematic barriers—as well as future directions for research and fair treatment of patients. At last, it emphasizes evidence-based approaches for putting these interventions into use to maximize patient results. More study is needed to guarantee that everyone has fair access to high-quality obesity treatment, understand the long-term consequences of new treatments, and enhance intervention procedures. © 2025 Elsevier B.V., All rights reserved.