Higher Disease and Pain Severity and Fatigue and Lower Balance Skills Are Associated With Higher Prevalence of Falling Among Individuals With the Inflammatory Disease of Neuromyelitis Optica Spectrum Disorder (Nmosd)

Higher Disease and Pain Severity and Fatigue and Lower Balance Skills Are Associated With Higher Prevalence of Falling Among Individuals With the Inflammatory Disease of Neuromyelitis Optica Spectrum Disorder (Nmosd) Publisher

Barzegar M^{1, 2} ; Bahmani DS^{3, 4, 5} ; Mirmosayyeb O^{1, 2} ; Azarbayejani R^{1, 6} ; Afsharisafavi A⁷ ; Vaheb S¹ ; Nehzat N¹ ; Dana A¹ ; Shaygannejad V^{1, 2} ; Motl RW³ ; Brand S^{4, 5, 8, 9, 10}

Show Affiliations

1. Isfahan Neurosciences Research Center, Alzahra Research Institute, Isfahan University of Medical Sciences, Isfahan, 81746-73461, Iran
2. Department of Neurology, Isfahan University of Medical Sciences, Isfahan, 81746-73461, Iran
3. Departments of Physical Therapy, University of Alabama at Birmingham, Birmingham, 35209, AL, United States
4. Center of Affective, Stress and Sleep Disorders (ZASS), University of Basel, Psychiatric Clinics (UPK), Basel, 4002, Switzerland
5. Sleep Disorders Research Center, Kermanshah University of Medical Sciences (KUMS), Kermanshah, 67198-51351, Iran
6. School of Medicine, Isfahan University of Medical Sciences, Isfahan, 81746-73441, Iran
7. Department of Biostatistics and Epidemiology, Faculty of Health, North Khorasan University of Medical Sciences, Bojnurd, 74877-94149, Iran
8. Substance Abuse Prevention Research Center, Health Institute, Kermanshah University of Medical Sciences (KUMS), Kermanshah, 67198-51351, Iran
9. School of Medicine, Tehran University of Medical Sciences (TUMS), Tehran, 14117-13135, Iran
10. Department of Sport, Exercise, and Health, Division of Sport Science and Psychosocial Health, University of Basel, Basel, 4051, Switzerland

Source: Journal of Clinical Medicine Published:2020

Abstract

Background: Neuromyelitis optica spectrum disorder (NMOSD) is a chronic inflammatory and autoimmune disorder that is associated with impaired vision, sensory loss, pain, fatigue, and spasms in the upper and lower limbs. Typically, persons with this disorder are also at higher risks of falls. Given this, the aims of the study were to compare the prevalence rates of falling for NMOSD cases and healthy controls (HCs), and to predict falling in the former group based on sociodemographic, psychological, and illness-related factors. Method: A total of 95 adults with NMOSD (Mean age = 34.89 years; 70.5% females) and 100 matched HCs took part in the study. All participants completed a series of questionnaires covering sociodemographic information and falling rates. The NMOSD individuals also reported on disease duration, pain, fatigue, and fear of falling, while their balance performance was objectively assessed. Results: Compared to healthy controls, the NMOSD cases had a 2.5-fold higher risk of falling. In this latter group, higher scores for pain, fatigue, fear of falling, and higher EDSS scores were distinguished between fallers and non-fallers, and objective balance skills had no predictive value. Conclusions: Compared to healthy controls, NMOSD sufferers had a 2.5-fold higher risk of experiencing falls. In this group, disease impairments (EDSS, fatigue, pain) predicted falling. Specific interventions such as regular resistance training might reduce the risk of falling. © 2020 by the authors. Licensee MDPI, Basel, Switzerland.

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Style	Citing Format
MLA	Barzegar M, et al.. "Higher Disease and Pain Severity and Fatigue and Lower Balance Skills Are Associated With Higher Prevalence of Falling Among Individuals With the Inflammatory Disease of Neuromyelitis Optica Spectrum Disorder (Nmosd)." Journal of Clinical Medicine, vol. 9, no. 11, 2020, pp. 1-12.
APA	Barzegar M, Bahmani DS, Mirmosayyeb O, Azarbayejani R, Afsharisafavi A, Vaheb S, Nehzat N, Dana A, Shaygannejad V, Motl RW, Brand S (2020). Higher Disease and Pain Severity and Fatigue and Lower Balance Skills Are Associated With Higher Prevalence of Falling Among Individuals With the Inflammatory Disease of Neuromyelitis Optica Spectrum Disorder (Nmosd). Journal of Clinical Medicine, 9(11), 1-12.
Chicago	Barzegar M, Bahmani DS, Mirmosayyeb O, Azarbayejani R, Afsharisafavi A, Vaheb S, Nehzat N, et al.. "Higher Disease and Pain Severity and Fatigue and Lower Balance Skills Are Associated With Higher Prevalence of Falling Among Individuals With the Inflammatory Disease of Neuromyelitis Optica Spectrum Disorder (Nmosd)." Journal of Clinical Medicine 9, no. 11 (2020): 1-12.
Harvard	Barzegar M et al. (2020) 'Higher Disease and Pain Severity and Fatigue and Lower Balance Skills Are Associated With Higher Prevalence of Falling Among Individuals With the Inflammatory Disease of Neuromyelitis Optica Spectrum Disorder (Nmosd)', Journal of Clinical Medicine, 9(11), pp. 1-12.
Vancouver	Barzegar M, Bahmani DS, Mirmosayyeb O, Azarbayejani R, Afsharisafavi A, Vaheb S, et al.. Higher Disease and Pain Severity and Fatigue and Lower Balance Skills Are Associated With Higher Prevalence of Falling Among Individuals With the Inflammatory Disease of Neuromyelitis Optica Spectrum Disorder (Nmosd). Journal of Clinical Medicine. 2020;9(11):1-12.
BibTex	@article{ author = {Barzegar M and Bahmani DS and Mirmosayyeb O and Azarbayejani R and Afsharisafavi A and Vaheb S and Nehzat N and Dana A and Shaygannejad V and Motl RW and Brand S}, title = {Higher Disease and Pain Severity and Fatigue and Lower Balance Skills Are Associated With Higher Prevalence of Falling Among Individuals With the Inflammatory Disease of Neuromyelitis Optica Spectrum Disorder (Nmosd)}, journal = {Journal of Clinical Medicine}, volume = {9}, number = {11}, pages = {1-12}, year = {2020} }
RIS	TY - JOUR AU - Barzegar M AU - Bahmani DS AU - Mirmosayyeb O AU - Azarbayejani R AU - Afsharisafavi A AU - Vaheb S AU - Nehzat N AU - Dana A AU - Shaygannejad V AU - Motl RW AU - Brand S TI - Higher Disease and Pain Severity and Fatigue and Lower Balance Skills Are Associated With Higher Prevalence of Falling Among Individuals With the Inflammatory Disease of Neuromyelitis Optica Spectrum Disorder (Nmosd) JO - Journal of Clinical Medicine VL - 9 IS - 11 SP - 1 EP - 12 PY - 2020 ER -

Style

Citing Format

MLA

Barzegar M, et al.. "Higher Disease and Pain Severity and Fatigue and Lower Balance Skills Are Associated With Higher Prevalence of Falling Among Individuals With the Inflammatory Disease of Neuromyelitis Optica Spectrum Disorder (Nmosd)." Journal of Clinical Medicine, vol. 9, no. 11, 2020, pp. 1-12.

APA

Barzegar M, Bahmani DS, Mirmosayyeb O, Azarbayejani R, Afsharisafavi A, Vaheb S, Nehzat N, Dana A, Shaygannejad V, Motl RW, Brand S (2020). Higher Disease and Pain Severity and Fatigue and Lower Balance Skills Are Associated With Higher Prevalence of Falling Among Individuals With the Inflammatory Disease of Neuromyelitis Optica Spectrum Disorder (Nmosd). Journal of Clinical Medicine, 9(11), 1-12.

Chicago

Barzegar M, Bahmani DS, Mirmosayyeb O, Azarbayejani R, Afsharisafavi A, Vaheb S, Nehzat N, et al.. "Higher Disease and Pain Severity and Fatigue and Lower Balance Skills Are Associated With Higher Prevalence of Falling Among Individuals With the Inflammatory Disease of Neuromyelitis Optica Spectrum Disorder (Nmosd)." Journal of Clinical Medicine 9, no. 11 (2020): 1-12.

Harvard

Barzegar M et al. (2020) 'Higher Disease and Pain Severity and Fatigue and Lower Balance Skills Are Associated With Higher Prevalence of Falling Among Individuals With the Inflammatory Disease of Neuromyelitis Optica Spectrum Disorder (Nmosd)', Journal of Clinical Medicine, 9(11), pp. 1-12.

Vancouver

Barzegar M, Bahmani DS, Mirmosayyeb O, Azarbayejani R, Afsharisafavi A, Vaheb S, et al.. Higher Disease and Pain Severity and Fatigue and Lower Balance Skills Are Associated With Higher Prevalence of Falling Among Individuals With the Inflammatory Disease of Neuromyelitis Optica Spectrum Disorder (Nmosd). Journal of Clinical Medicine. 2020;9(11):1-12.

BibTex

@article{ author = {Barzegar M and Bahmani DS and Mirmosayyeb O and Azarbayejani R and Afsharisafavi A and Vaheb S and Nehzat N and Dana A and Shaygannejad V and Motl RW and Brand S}, title = {Higher Disease and Pain Severity and Fatigue and Lower Balance Skills Are Associated With Higher Prevalence of Falling Among Individuals With the Inflammatory Disease of Neuromyelitis Optica Spectrum Disorder (Nmosd)}, journal = {Journal of Clinical Medicine}, volume = {9}, number = {11}, pages = {1-12}, year = {2020} }

RIS

TY - JOUR
AU - Barzegar M
AU - Bahmani DS
AU - Mirmosayyeb O
AU - Azarbayejani R
AU - Afsharisafavi A
AU - Vaheb S
AU - Nehzat N
AU - Dana A
AU - Shaygannejad V
AU - Motl RW
AU - Brand S
TI - Higher Disease and Pain Severity and Fatigue and Lower Balance Skills Are Associated With Higher Prevalence of Falling Among Individuals With the Inflammatory Disease of Neuromyelitis Optica Spectrum Disorder (Nmosd)
JO - Journal of Clinical Medicine
VL - 9
IS - 11
SP - 1
EP - 12
PY - 2020
ER -

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Abstract