Swi/Snf Complex, Promising Target in Melanoma Therapy: Snapshot View

Swi/Snf Complex, Promising Target in Melanoma Therapy: Snapshot View Publisher

Mollapour Sisakht M^{1, 2} ; Amirkhani MA³ ; Nilforoushzadeh MA³

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1. Biotechnology Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
2. Department of Biochemistry, Erasmus University Medical Center, Rotterdam, Netherlands
3. Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran

Source: Frontiers in Medicine Published:2023

Abstract

Therapeutic strategies based on epigenetic regulators are rapidly increasing in light of recent advances in discovering the role of epigenetic factors in response and sensitivity to therapy. Although loss-of-function mutations in genes encoding the SWItch/Sucrose NonFermentable (SWI/SNF) subunits play an important role in the occurrence of ~34% of melanomas, the potential of using inhibitors and synthetic lethality interactions between key subunits of the complex that play an important role in melanoma progression must be considered. Here, we discuss the importance of the clinical application of SWI/SNF subunits as a promising potential therapeutic in melanoma. Copyright © 2023 Mollapour Sisakht, Amirkhani and Nilforoushzadeh.

Experts (# of related papers)

Mohammad Abdollahi (1)

Style	Citing Format
MLA	Mollapour Sisakht M, Amirkhani MA, Nilforoushzadeh MA. "Swi/Snf Complex, Promising Target in Melanoma Therapy: Snapshot View." Frontiers in Medicine, vol. 10, no. , 2023, pp. -.
APA	Mollapour Sisakht M, Amirkhani MA, Nilforoushzadeh MA (2023). Swi/Snf Complex, Promising Target in Melanoma Therapy: Snapshot View. Frontiers in Medicine, 10(), -.
Chicago	Mollapour Sisakht M, Amirkhani MA, Nilforoushzadeh MA. "Swi/Snf Complex, Promising Target in Melanoma Therapy: Snapshot View." Frontiers in Medicine 10, no. (2023): -.
Harvard	Mollapour Sisakht M, Amirkhani MA, Nilforoushzadeh MA (2023) 'Swi/Snf Complex, Promising Target in Melanoma Therapy: Snapshot View', Frontiers in Medicine, 10(), pp. -.
Vancouver	Mollapour Sisakht M, Amirkhani MA, Nilforoushzadeh MA. Swi/Snf Complex, Promising Target in Melanoma Therapy: Snapshot View. Frontiers in Medicine. 2023;10():-.
BibTex	@article{ author = {Mollapour Sisakht M and Amirkhani MA and Nilforoushzadeh MA}, title = {Swi/Snf Complex, Promising Target in Melanoma Therapy: Snapshot View}, journal = {Frontiers in Medicine}, volume = {10}, number = {}, pages = {-}, year = {2023} }
RIS	TY - JOUR AU - Mollapour Sisakht M AU - Amirkhani MA AU - Nilforoushzadeh MA TI - Swi/Snf Complex, Promising Target in Melanoma Therapy: Snapshot View JO - Frontiers in Medicine VL - 10 IS - SP - EP - PY - 2023 ER -

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