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Application of Graphene Materials in Molecular Diagnostics



Salehnia F1 ; Fakhri N2 ; Hosseini M3 ; Ganjali MR1, 4
Authors
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Authors Affiliations
  1. 1. Center of Excellence in Electrochemistry, Faculty of Chemistry, University of Tehran, Tehran, Iran
  2. 2. School of Chemical Engineering, College of Engineering, University of Tehran, Tehran, Iran
  3. 3. Department of Life Science Engineering, Faculty of New Sciences & Technologies, University of Tehran, Tehran, Iran
  4. 4. Biosensor Research Center, Endocrinology & Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran

Source: Handbook of Graphene Published:2019

Abstract

This chapter addresses the initial steps one has to give to explore the unique properties of graphene materials in molecular diagnostics. There is significant interest in using graphene and its derivative materials for various early diagnosis of life-threatening diseases and real-time health monitoring. The unique physicochemical properties, excellent electrical conductivity, optical properties, biocompatibility, ease of functionalization, and flexibility could be of great value for creating advanced biosensors and diagnostics platforms. Following an introduction and discussion on the significance of fabrication protocols and assembly, this chapter is intended to assess why graphene materials are suitable to build better medical diagnostics platforms, the working of existing diagnostics schemes, and their current status toward commercialization for wearable diagnostic and prognostic devices. We believe that this chapter will provide critical insight for harnessing graphene materials as a suitable biosensor for the clinical diagnostics, its prospects, and challenges ahead. © 2019 John Wiley & Sons, Inc. All rights reserved.
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