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Molecular Evidence of Role of Vitamin D Deficiency in Various Extraskeletal Diseases Publisher Pubmed



Zendehdel A1 ; Arefi M2
Authors

Source: Journal of Cellular Biochemistry Published:2019


Abstract

Background: Role of vitamin D is not only limited to skeletal system but various other systems of the body, such as immune system, endocrine system, and cardiopulmonary system. Materials and Methods: It is supported by the confirmations of systems-wide expression of vitamin D receptor (VDR), endocrinal effect of calcitriol, and its role in immune responses. Results: Expression of VDR in various systems, immunoregulatory and hormonal response of vitamin D and deficiency of vitamin D may establish various pathologies in the body. Conclusion: This review provides molecular evidence of relation of vitamin D with extra skeletal. © 2019 Wiley Periodicals, Inc.
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