Bonding to Molar-Incisor Hypomineralization Affected Teeth: A Scoping Review of Adhesive Strategies, in Vitro Performance, and Clinical Outcomes Publisher

Summary: Can young teeth with Molar-Incisor Hypomineralization be effectively treated? A review finds etch-and-rinse adhesives outperformed others. Adhesive choice is vital! #DentalHealth #MIHmanagement

Khorandi F M ; Moradi S ; Tayebi G ; Hooshmand T
Source: Frontiers in Dentistry Published:2026

Abstract

Molar-incisor hypomineralization (MIH) poses major restorative challenges due to compromised enamel and its reduced bonding capacity. This scoping review evaluated treatment options for MIH-affected young permanent teeth following PRISMA-ScR guidelines. A systematic search in PubMed, Cochrane, Science Direct and gray literature identified 21 eligible studies published between 2013 and 2025, including in-vitro and clinical studies. Laboratory findings demonstrated lower bond strengths in MIH enamel compared with the sound enamel. Etch-and-rinse adhesives performed more reliably than that of self-etch systems, while pretreatment procedures improved adhesion in some settings. Clinical studies showed resin-based sealants and composites bonded with etch-and-rinse adhesives achieved higher retention. Glass ionomer and glass hybrid restorations offered mostly short-term success and are best used as an interim option. Investigated indirect restorations provided superior longevity in severe cases. Preventive adjuncts such as applying varnishes reduced hypersensitivity and caries risk. Finally, this review highlights the central role of adhesive performance in MIH management. © 2026 The Authors. Published by Tehran University of Medical Sciences.