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Evaluation of Morphine, Methadone, Digoxin, and Dronabinol Poisoning During the Years 2017 to 2019 in Ilam, Iran Publisher



Saki K1 ; Bahmani M2 ; Zamanian G3, 4 ; Abbasi N2, 5 ; Aidy A2 ; Manouchehri A6 ; Mandal SK7 ; Ganguly P8 ; Shokri S9
Authors
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Authors Affiliations
  1. 1. Department of Psychiatry, School of Medicine, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  2. 2. Biotechnology and Medicinal Plants Research Center, Ilam University of Medical Sciences, Ilam, Iran
  3. 3. Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Department of Pharmacology, Ilam University of Medical Sciences, Ilam, Iran
  6. 6. Department of Internal Medicine, Shahid Beheshti Hospital, Babol University of Medical Sciences, Babol, Iran
  7. 7. Dr B.C. Roy College of Pharmacy and Allied Health Sciences, Meghnad Saha Sarani, Bidhan Nagar, West Bengal, Durgapur, 713206, India
  8. 8. Department of Pharmaceutical Technology, Brainware University, 398- Ramkrishnapur Road, Barasat, West Bengal, Kolkata, 700125, India
  9. 9. Department of Environmental Health Engineering, Division of Food Safety and Hygiene, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

Source: Caspian Journal of Internal Medicine Published:2023


Abstract

Background: Every year, drug poisoning is the most prevalent reason for referring patients to medical centers. This study aimed to evaluation of morphine, methadone, digoxin, and dronabinol poisoning in Shahid Mostafa Khomeini Hospital in Ilam. Methods: In this In this Cross-sectional study, patient samples suspected of morphine, methadone, digoxin, and dronabinol poisoning referred to the toxicology laboratory of Ilam University of Medical Sciences were analyzed using the HPLC method, and the results were analysed using SPSS software. Results: Results showed that the percentage of drug use is greater in men than in women. The highest percentage of morphine and methadone poisonings were detected in those under the age of 40, whereas the highest percentage of digoxin poisonings were recorded in those over the age of 80. As a result, the average age of digoxin users was substantially greater in men than in women. Methadone consumers showed significantly greater blood levels than others. In addition, there was a significant difference (P<0.01) in blood levels between men and women who used morphine. Conclusion: In general, it is important to understand the status of drug poisoning with drugs such as morphine, methadone, digoxin, and dronabinol, as well as the prognosis associated with the treatment process of such poisoning. © 2022 The Author(s).
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