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Sulfur Mustard Exposure and Non-Ischemic Central Retinal Vein Occlusion



Shoeibi N1, 2 ; Balalimood M3, 4 ; Abrishami M5
Authors
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Authors Affiliations
  1. 1. Retina Research Center, Department of Ophthalmology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
  2. 2. Eye Research Center, Department of Ophthalmology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
  3. 3. Medical Toxicology Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
  4. 4. Department of Clinical Toxicology, Imam Reza Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
  5. 5. Eye Research Center, Department of Retina and Vitreous, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran

Source: Iranian Journal of Medical Sciences Published:2016

Abstract

A 41-year-old man was referred with a complaint of visual loss in his left eye and his best corrected visual acuity was 20/80. Slit lamp examination showed arborizing conjunctival vessels and dry eye. Fundus examination and fluorescein angiography revealed a non-ischemic central retinal vein occlusion. Cardiovascular, rheumatologic, and hematologic work up showed no abnormal findings. An ascertained history of exposure to sulfur mustard during the Iran-Iraq war was documented in his medical history. Four sessions of intravitreal bevacizumab injections were done as needed. After two-year follow-up, visual acuity in his left eye improved to 20/25 and macular edema was resolved without any need for further interventions. We conclude that sulfur mustard gas exposure may be considered as a predisposing factor for central retinal vein occlusion, as was found in our patient (an Iranian war veteran) by excluding all yet known etiologies and predisposing factors. © 2016, Shiraz University of Medical Sciences. All rights reserved.