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Advice on Assistance and Protection Provided by the Scientific Advisory Board of the Organisation for the Prohibition of Chemical Weapons: Part 3. on Medical Care and Treatment of Injuries From Sulfur Mustard Publisher Pubmed



Timperley CM1 ; Forman JE2 ; Abdollahi M3 ; Alamri AS4 ; Baulig A5 ; Benachour D6 ; Borrett V7 ; Carino FA8 ; Curty C9 ; Geist M10 ; Gonzalez D11 ; Kane W12 ; Kovarik Z13 ; Martinezalvarez R14 Show All Authors
Authors
  1. Timperley CM1
  2. Forman JE2
  3. Abdollahi M3
  4. Alamri AS4
  5. Baulig A5
  6. Benachour D6
  7. Borrett V7
  8. Carino FA8
  9. Curty C9
  10. Geist M10
  11. Gonzalez D11
  12. Kane W12
  13. Kovarik Z13
  14. Martinezalvarez R14
  15. Mourao NMF15
  16. Neffe S16
  17. Raza SK17
  18. Rubaylo V18
  19. Suarez AG19
  20. Takeuchi K20
  21. Tang C21
  22. Trifiro F22
  23. Van Straten FM23
  24. Vanninen PS24
  25. Vucinic S25
  26. Zaitsev V26
  27. Zafaruzzaman M27
  28. Zina MS28
  29. Holen S29
  30. Alwan WS30
  31. Suri V31
  32. Hotchkiss PJ32
  33. Ghanei M33
Show Affiliations
Authors Affiliations
  1. 1. Chair of the OPCW SAB from 2015-2018, Defence Science and Technology Laboratory (Dstl), Porton Down, Salisbury, Wiltshire, United Kingdom
  2. 2. Science Policy Adviser and Secretary to the SAB, OPCW, The Hague, 2417, JR, Netherlands
  3. 3. Toxicology and Diseases Group, The Institute of Pharmaceutical Sciences (TIPS) and Department of Toxicology and Pharmacology, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Saudi Basic Industries Corporation (SABIC), Riyadh, Saudi Arabia
  5. 5. Secretariat General de la Defense et de la Securite Nationale (SGDSN), Paris, France
  6. 6. LMPMP, Faculty of Technology, Ferhat Abbas University, Setif-1, Algeria
  7. 7. La Trobe Institute for Agriculture and Food, La Trobe University, Victoria, 3086, Australia
  8. 8. University of the Philippines, Quezon City, Philippines
  9. 9. Spiez Laboratory, Spiez, Switzerland
  10. 10. BASF SE, Ludwigshafen, Germany
  11. 11. Facultad De Quimica, Universidad de la Republica, Montevideo, Uruguay
  12. 12. Consultant to Monsanto Company, LA, United States
  13. 13. Institute for Medical Research and Occupational Health, Zagreb, Croatia
  14. 14. Complutense University, Madrid, Spain
  15. 15. Brazilian Chemical Industry, Sao Paulo, Brazil
  16. 16. Military University of Technology, Warsaw, Poland
  17. 17. Chairperson Accreditation Committee, National Accreditation Board for Testing and Calibration Laboratories (NABL), India
  18. 18. State Scientific Research Institute of Organic Chemistry and Technology (GosNIIOKhT), Moscow, Russian Federation
  19. 19. Universidad Nacional de Rosario, Consejo Nacional de Investigaciones Cientificas y Tecnicas, Rosario, Argentina
  20. 20. National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, Japan
  21. 21. Office for the Disposal of Japanese Abandoned Chemical Weapons, Ministry of National Defence, Beijing, China
  22. 22. Department of Industrial Chemistry, University of Bologna, Bologna, Italy
  23. 23. Independent Former OPCW SAB Member, South Africa
  24. 24. VERIFIN, Department of Chemistry, Faculty of Science, University of Helsinki, Helsinki, Finland
  25. 25. National Poison Control Centre, Military Medical Academy, Belgrade, Serbia
  26. 26. Pontifical Catholic University of Rio de Janeiro, Brazil
  27. 27. National Engineering and Scientific Commission (NESCOM), Islamabad, Pakistan
  28. 28. Faculty of Sciences of Tunis (FST), Tunis, Tunisia
  29. 29. Head of Strategy and Policy at the OPCW from 2009 to 2015
  30. 30. Medicinal Chemistry Department, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, 3052, Victoria, Australia
  31. 31. Intern in the OPCW Office of Strategy and Policy, Summer 2018
  32. 32. Senior Science Policy Officer and Secretary to the SAB, OPCW, The Hague, 2417, JR, Netherlands
  33. 33. Chemical Injuries Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran

Source: Toxicology Published:2021


Abstract

Blister agents damage the skin, eyes, mucous membranes and subcutaneous tissues. Other toxic effects may occur after absorption. The response of the Scientific Advisory Board (SAB) of the Organisation for the Prohibition of Chemical Weapons (OPCW) to a request from the OPCW Director-General in 2013 on the status of medical countermeasures and treatments to blister agents is updated through the incorporation of the latest information. The physical and toxicological properties of sulfur mustard and clinical effects and treatments are summarised. The information should assist medics and emergency responders who may be unfamiliar with the toxidrome of sulfur mustard and its treatment. © 2021
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