Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
The Frequency of Osteomyelitis After Pressure Injury in Spinal Cord Injury: A Systematic Review and Meta-Analysis Publisher Pubmed



Jangholi E1, 2, 3 ; Alizadeh SD1 ; Farahbakhsh F1, 3, 4 ; Baigi V1, 5 ; Ghodsi Z1, 2 ; Mahdavi Sharif P1 ; Ghashghaei S1, 6 ; Abbaszadeh M1, 6 ; Zeinaddini Meymand A1 ; Eskandari Z7 ; Rahimimovaghar V1, 8
Authors
Show Affiliations
Authors Affiliations
  1. 1. Sina Trauma and Surgery Research Center, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Brain and Spinal Cord Injury Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Neurosurgery, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Sports Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Department of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran
  7. 7. Department of Management, Faculty of Social Sciences and Economics, Alzahra University, Tehran, Iran
  8. 8. Universal Scientific Education and Research Network (USERN), Tehran, Iran

Source: Spinal Cord Series and Cases Published:2024


Abstract

Study design: A systematic review and meta-analysis Objective: To determine the global frequency of osteomyelitis in individuals with spinal cord injury who have pressure injuries (SCI-PI). Methods: A comprehensive search on PubMed, EMBASE, Scopus, and the Web of Science has been conducted until November 2023. The Cochrane Handbook for Systematic Reviews was followed. Cohort and cross-sectional studies included SCI-PI participants who reported the frequency of osteomyelitis without language restriction. Data extraction was performed by four reviewers in two groups. We used the Newcastle-Ottawa Quality Assessment Scale for quality assessment. The Chi-squared and I2 tests were applied to detect heterogeneity between studies. Also, a random-effects model was performed for the report data. Results: Ten out of 986 studies met our eligibility criteria, with 492 SCI-PI individuals. It was discovered that most SCIs were thoracolumbar injuries and male. There was a history of PI in more than half the patients. SCI was primarily caused by trauma. A meta-analysis revealed a significantly heterogeneous 43.0% osteomyelitis frequency. There was no evidence of publication bias. Subgroup analysis based on study quality revealed that the frequency of osteomyelitis in low-quality studies was 34.5%, whereas the frequency in high-quality research was 47.4%. Furthermore, the overall frequency of osteomyelitis was 29.0% in the subgroup analysis of research carried out in the USA. Conclusions: Our study highlights the significant burden of osteomyelitis among SCI-PI individuals. These findings underscore the pressing need for standardized diagnostic and management protocols to mitigate the morbidity associated with osteomyelitis in this vulnerable population. © The Author(s), under exclusive licence to International Spinal Cord Society 2024.
Related Docs
1. Pressure Ulcers and Acute Risk Factors in Individuals With Traumatic Spinal Fractures With or Without Spinal Cord Injuries: A Prospective Analysis of the National Spinal Column/Cord Injury Registry of Iran (Nscir-Ir) Data, Chinese Journal of Traumatology - English Edition (2023)
2. Association of Overweight and Obesity With the Prevalence and Incidence of Pressure Ulcers: A Systematic Review and Meta-Analysis, Clinical Nutrition (2021)
3. Predictive Value of Braden Risk Factors in Pressure Ulcers of Outpatients With Spinal Cord Injury, Acta Medica Iranica (2018)
Experts (# of related papers)
View all Related Experts
Mehdi Yaseri (1)
Mohammad Javad Hosseinzadeh Attar (1)