Salvia Officinalis Extract Mediated for the Synthesis of So-Mgo-Nps and Their Utilization for Simultaneous Measurement of Dopamine, Uric Acid, and Ascorbic Acid by Voltammetry Method Publisher



Soltani N¹ ; Ebrahimian J² ; Khayatkashani M^{3, 4} ; Tavakkoli N¹ ; Salavatiniasari M² Show Affiliations
Source: Journal of Molecular Liquids Published:2021

Abstract

Magnesium oxide nanoparticles were fabricated using green synthesis with salvia officinalis (SO) leaf extract. SO-MgO-NPs were detected using fourier transform infrared spectroscopy (FT-IR), energy dispersive X-Ray spectroscopy (EDX), field emission scanning electron microscopy (FE-SEM), and X-ray diffraction (XRD). SO-MgO-NPs were used to making a modified carbon paste electrode (CPE), abbreviated by the name SO-MgO-NPs-CPE. This electrode was successfully utilized for the measurement of dopamine (DA), uric acid (UA), and ascorbic acid (AA) using electrochemical techniques such as cyclic voltammetry (CV) and differential pulse voltammetry (DPV) methods. Excellent electrocatalytic activity of SO-MgO-NPs allows selective the measurement of DA in the presence of UA and AA by the voltammetric method so that the peak oxidation potential distances ΔEp for AA-DA, and DA-UA is about 260 mV and 200 mV, respectively. The SO-MgO-NPs were used to measure DA, UA, and AA in actual samples such as pharmaceutical samples and healthy samples of human blood serum, and good results were obtained. © 2021 Elsevier B.V.