The Wonders of Stem Cells Therapeutic Application Towards Chronic Obstructive Pulmonary Disease Publisher Pubmed



Tayanloobeik A¹ ; Kokabi Hamidpour S² ; Chaharbor M¹ ; Rezaeitavirani M³ ; Arjmand R¹ ; Adibi H⁴ ; Ojagh H⁵ ; Larijani B⁶ ; Arjmand B¹ Show Affiliations
Source: Pulmonary Pharmacology and Therapeutics Published:2023

Abstract

Chronic obstructive pulmonary disease (COPD) is a respiratory condition characterized by its heterogeneous nature, progressive course, and significant impact on individuals' quality of life. It is a prevalent global health issue affecting a substantial number of individuals and can pose life-threatening complications if left unmanaged. The development and course of COPD can be influenced by a range of risk factors, including genetic predisposition and environmental exposures. Nevertheless, as researchers adopt a more comprehensive and expansive viewpoint of therapeutic techniques, the associated obstacles become more apparent. Indeed, a definitive medication for COPD that reliably leads to symptom alleviation has not yet been discovered. Therefore, the limitations of conventional therapy methods prompted researchers to focus on the advancement of novel procedures, potentially leading to significant outcomes. In contemporary times, the field of regenerative medicine and cell therapy has presented unprecedented opportunities for the exploration of innovative treatments for COPD, owing to the distinctive attributes exhibited by stem cells. Hence, it is imperative to provide due consideration to preclinical investigations and notable characteristics of stem cells as they serve as a means to comprehensively comprehend the fundamental mechanisms of COPD and uncover novel therapeutic strategies with enhanced efficacy for patients. © 2023