Prenatal Mercury Exposure and Birth Weight

Prenatal Mercury Exposure and Birth Weight Publisher Pubmed

Vigeh M^{1, 2} ; Nishioka E^{2, 4} ; Ohtani K³ ; Omori Y⁵ ; Matsukawa T² ; Koda S³ ; Yokoyama K²

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1. Maternal, Fetal, and Newborn Research Center, Tehran University of Medical Sciences, Vali-e-Asr Hospital, Keshavarz Bul., Tehran, 1419733141, Iran
2. Department of Epidemiology and Environmental Health, Juntendo University Faculty of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan
3. Occupational Epidemiology, National Institute of Occupational Safety and Health, 6-21-1 Nagao, Tama-ku, Kawasaki, 204-0024, Kanagawa, Japan
4. Department of Maternal Nursing, Division of Nursing, National Defense Medical College, 3-2 Namiki, Tokorozawa, 359-8543, Saitama, Japan
5. Department of Preventive Medicine and Public Health, Kitasato University School of Medicine, 1-15-1, Kitazato, Minami-ku, Sagamihara, 252-0373, Kanagawa, Japan

Source: Reproductive Toxicology Published:2018

Abstract

Adverse effects of prenatal mercury exposure on pregnancy outcomes remain a public health concern. We assessed the relationship between prenatal mercury exposure and newborn anthropometric characteristics in 334 mother-child pairs from the early stages of pregnancy to delivery in Tokyo, Japan, between December 2010 and October 2012. We found a negative correlation between blood mercury levels during the first and second trimesters of gestation and birth weight (r = −0.134 and −0.119, respectively; p < 0.05). Multiple linear regression analysis confirmed the relationship between first-trimester maternal blood mercury levels and birth weight when adjusted for independent variables (β = −0.170, t = −2.762; p = 0.006). Mean mercury levels in umbilical cord blood were twice as high as maternal blood levels (10.15 ± 7.74 and 4.97 ± 3.25 μg/L, respectively; r = 0.974, p < 0.001). Our findings suggest that pregnant women and women of reproductive age should avoid mercury exposure, even at low levels, because of its potentially adverse effects on fetal development. © 2018 Elsevier Inc.

Style	Citing Format
MLA	Vigeh M, et al.. "Prenatal Mercury Exposure and Birth Weight." Reproductive Toxicology, vol. 76, no. , 2018, pp. 78-83.
APA	Vigeh M, Nishioka E, Ohtani K, Omori Y, Matsukawa T, Koda S, Yokoyama K (2018). Prenatal Mercury Exposure and Birth Weight. Reproductive Toxicology, 76(), 78-83.
Chicago	Vigeh M, Nishioka E, Ohtani K, Omori Y, Matsukawa T, Koda S, Yokoyama K. "Prenatal Mercury Exposure and Birth Weight." Reproductive Toxicology 76, no. (2018): 78-83.
Harvard	Vigeh M et al. (2018) 'Prenatal Mercury Exposure and Birth Weight', Reproductive Toxicology, 76(), pp. 78-83.
Vancouver	Vigeh M, Nishioka E, Ohtani K, Omori Y, Matsukawa T, Koda S, et al.. Prenatal Mercury Exposure and Birth Weight. Reproductive Toxicology. 2018;76():78-83.
BibTex	@article{ author = {Vigeh M and Nishioka E and Ohtani K and Omori Y and Matsukawa T and Koda S and Yokoyama K}, title = {Prenatal Mercury Exposure and Birth Weight}, journal = {Reproductive Toxicology}, volume = {76}, number = {}, pages = {78-83}, year = {2018} }
RIS	TY - JOUR AU - Vigeh M AU - Nishioka E AU - Ohtani K AU - Omori Y AU - Matsukawa T AU - Koda S AU - Yokoyama K TI - Prenatal Mercury Exposure and Birth Weight JO - Reproductive Toxicology VL - 76 IS - SP - 78 EP - 83 PY - 2018 ER -

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